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ProteomicseIF3 subunit-specific mRNA selectivity profiling reveals eIF3k as a cancer-relevant regulator of ribosome content
eIF3, whose subunits are frequently overexpressed in cancer, regulates mRNA translation from initiation to termination, but mRNAeIF3, whose subunits are frequently overexpressed in cancer, regulates mRNA translation from initiation to termination, but mRNA-selective functions of individual subunits ...
ORGANISM(S): Homo sapiens (Human) 
2023-03-14 | PXD034084 | Pride
Eif3 
MetabolomicsGut microbiota production of trimethyl-5-aminovaleric acid reduces fatty acid oxidation and accelerates cardiac hypertrophy
Numerous studies found intestinal microbiota alterations which are thought to affect the development of various diseases through the production of gut-derived metabolites. However, the specific metabolites and their pathophysiological contribution to cardiac hypertrophy or heart failure progression ...
2021-12-08 | MTBLS3174 | MetaboLights
TranscriptomicsNext generation sequencing for patients with hypomyelinating leukodystrophies
Targeted enrichment-based next-generation sequencing or whole exome sequencing were taken for patients with hypomyelinating leukodystrophies to reveal genetic aetiologies. All genomic DNA used in the experiments was extracted from the peripheral leukocytes. A complete kit was synthetized using the A...
ORGANISM(S): Homo sapiens 
2018-02-01 | E-MTAB-6054 | biostudies-arrayexpress
MetabolomicsAdaptation of gut microbiome and host metabolic systems to lignocellulosic degradation in bamboo rats

Bamboo rats (Rhizomys pruinosus) are among the few mammals that lives on a bamboo-based diet which is mainly composed of lignocellulose. However, the mechanisms of adaptation of their gut microbiome and metabolic systems in the degradation of lignocellulose are largely unknown. Here, we ...

2022-04-22 | MTBLS4161 | MetaboLights
ProteomicsGut microbiota production of N,N,N-trimethyl-5-aminovaleric acid reduces fatty acid oxidation and accelerates cardiac hypertrophy in diet-induced obesity
Numerous studies found intestinal microbiota alterations which are thought to affect the development of various diseases through the production of gut-derived metabolites. However, the specific metabolites and their pathophysiological contribution to cardiac hypertrophy or heart failure progression ...
ORGANISM(S): Mus Musculus 
2021-09-08 | PXD028230 |
UnknownRobust estimation of bacterial cell count from optical density.
Not available
S-EPMC7499192 | biostudies-literature
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