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ProteomicsSupporting raw MS data for paper (doi:10.1038/s41589-025-01894-4) by Raiff A., Zhao Z. et al (2025), titled "TOM20-Driven E3 Ligase Recruitment Regulates Mitochondrial Dynamics Through PLD6"
Supporting raw MS data for paper (doi:10.1038/s41589-025-01894-4) by Raiff A., Zhao Z. et al (2025), titled "TOM20-Driven E3 Ligase Recruitment Regulates Mitochondrial Dynamics Through PLD6". Index of MS files and labels Supplementary Table 1 - HEK293T - Proteome (CZ-1-23 | Unimod:35; 737; 4 | 126 -...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2024-08-23 | MSV000095689 | MassIVE
ProteomicsBioE3 enables the identification of bona fide targets of E3 ligases
The post-translational modification of proteins by ubiquitination is a highly regulated process that involves a dynamic, three-step enzymatic cascade, where more than 600 E3 ligases play a critical role in recognizing specific substrates for modification. Separating bona fide targets of E3s from E3-...
ORGANISM(S): Homo sapiens (Human) 
2024-01-26 | PXD041685 | Pride
E3-ligases Bioe3 Ubiquitination Proteomics 
GenomicsCombinatorial mapping of E3 ubiquitin ligases to their target substrates
Combinatorial mapping of E3 ubiquitin ligases to their target substrates
PRJNA982147 | ENA
ProteomicsRepurposing E3 ubiquitin ligases as cell surface protein degraders using Proteolysis Targeting Antibodies
The majority of current therapeutics targeting plasma membrane receptors function by antagonizing ligand binding or enzymatic activities. Typical mammalian proteins, however, consist of multiple domains executing discrete but coordinated activities, and saturating inhibition of one functional domain...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2022-05-25 | MSV000089542 | MassIVE
GenomicsSIAH ubiquitin E3 ligases as modulators of inflammatory gene expression
SIAH ubiquitin E3 ligases as modulators of inflammatory gene expression
PRJNA742677 | ENA
ProteomicsmTORC1 regulates the pyrimidine salvage pathway by controlling UCK2 turnover via the CTLH-WDR26 E3 ligase
Supporting MS data for paper (DOI:10.1016/j.celrep.2024.115179) by Pham, B. et al., titled "mTORC1 regulates the pyrimidine salvage pathway by controlling UCK2 turnover via the CTLH-WDR26 E3 ligase". Related to Table S1 - HEK293 - degradomics (HA-2-165 | Unimod:35; 2016; 4 | 126 - Neg Ctrl (WT cells...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2024-08-29 | MSV000095724 | MassIVE
GenomicsNt-acetylation independent turnover of SQUALENE EPOXIDASE 1 by Arabidopsis DOA10-like E3 ligases
Nt-acetylation independent turnover of SQUALENE EPOXIDASE 1 by Arabidopsis DOA10-like E3 ligases
PRJNA989617 | ENA
GenomicsRepurposing E3 ubiquitin ligases as cell surface protein degraders using Proteolysis Targeting Antibodies
Repurposing E3 ubiquitin ligases as cell surface protein degraders using Proteolysis Targeting Antibodies
PRJNA859706 | ENA
ProteomicsUFM1 E3 ligase promotes recycling of 60S ribosomal subunits from the ER
Supporting MS data for paper (doi: 10.1038/s41586-024-07073-0) by DaRosa P.A., Penchev I. et al., titled "UFM1 E3 ligase promotes recycling of 60S ribosomal subunits from the ER". Index of MS supporting files uploaded: Related to Related to Fig. 1b, c (xb01004(UFM1), xb01005(SBP-UFM1): LFQ IP-MS (Un...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2023-12-22 | MSV000093721 | MassIVE
ProteomicsUFM1 E3 ligase promotes recycling of 60S ribosomal subunits from the ER
Supporting MS data for paper (doi: 10.1038/s41586-024-07073-0) by DaRosa P.A., Penchev I. et al., titled "UFM1 E3 ligase promotes recycling of 60S ribosomal subunits from the ER". Index of MS supporting files uploaded: - Related to Fig. 1a and Extended Data Fig. 1a (AO3435-AO3440: TMT proteomics (Un...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2023-11-27 | MSV000093510 | MassIVE
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