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ProteomicsEnhancing glycopeptide annotation and glycan localization using the EAD implementation of hot electron capture dissociation through a multiplexed parallel reaction monitoring design of experiment
We present an optimized electron activated dissociation (EAD) methodology for liquid chromatography-tandem mass spectrometry (LC-MS/MS) based characterization of N- and O-glycopeptides. Recombinant human erythropoietin (rhEPO) was used as a model glycoprotein in this study. Applying a full factorial...
ORGANISM(S): Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) 
2025-10-23 | PXD063177 | Pride
Glycoproteomics Parallel reaction monitoring Electron activated dissociation Design of experiments Lc-ms/ms 
ProteomicsElectron-Activated Dissociation and Collision-Induced Dissociation Glycopeptide Fragmentation for Improved Glycoproteomics
Protein glycosylation is a critical PTM for the stability and biological function of many proteins, but full characterisation of site-specific glycosylation of proteins remains analytically challenging. Collision induced dissociation (CID) is the most common fragmentation method used in LC-MS/MS wor...
ORGANISM(S): Homo sapiens (Human) 
2024-07-04 | PXD050173 | Pride
Cid Glycopeptide Ead Zenotof 7600 
UnknownPrediction of Graft Survival Post-liver Transplantation by L-GrAFT Risk Score Model, EASE Score, MEAF Scoring, and EAD.
Not available
S-EPMC8641658 | biostudies-literature
UnknownLibGen: Generating High Quality Spectral Libraries of Natural Products for EAD-, UVPD-, and HCD-High Resolution Mass Spectrometers.
Not available
S-EPMC11492814 | biostudies-literature
GenomicsSCENIC+: identification of enhancers and gene regulatory networks using single-cell multiomics (EAD)
SCENIC+: identification of enhancers and gene regulatory networks using single-cell multiomics (EAD)
PRJNA867354 | ENA
TranscriptomicsTranscriptional response to Activating transcription factor 3 (Atf3) activity in the Drosophila eye antenna imaginal disc (EAD) epithelium.
Here we describe the transcriptional response to Atf3 expression in the EAD. Atf3 is a cell polarity response gene acting downstream of the membrane-associated Scribble polarity complex. Loss of the neoplastic tumor suppressors Scribble or Dlg1 induces Atf3 expression via aPKC signaling. Using ChIP-...
ORGANISM(S): Drosophila melanogaster 
2018-02-20 | GSE89845 | GEO
TranscriptomicsA single-cell landscape of human liver transplantation reveals a pathogenic immune niche associated with early allograft dysfunction
Liver transplantation (LT) is the standard therapy for individuals afflicted with end-stage liver disease. Despite notable advancements in LT technology during recent decades, the incidence of early allograft dysfunction (EAD) remains a critical concern, exacerbating the current organ shortage and d...
ORGANISM(S): Homo sapiens 
2021-12-16 | GSE189539 | GEO
UnknownIn-vitro metabolite identification for MEDI7219, an oral GLP-1 analog, using LC-MS/MS with CID and EAD approaches.
Not available
S-EPMC12369624 | biostudies-literature
TranscriptomicsCell-free transcriptome of Barrett’s Esophagus and Esophageal Cancer [Illumina - short read]
Esophageal adenocarcinoma (EAD) benefits from a large improvement in five-year survival when detected in early stages, therefore, early detection strategies are paramount to mitigating disease. Those diagnosed with Barrett’s Esophagus (BE) are at higher risk for EAD, though there exists no routine s...
ORGANISM(S): Homo sapiens 
2025-12-08 | GSE271390 | GEO
TranscriptomicsCell-free transcriptome of Barrett’s Esophagus and Esophageal Cancer [Nanopore - long read]
Esophageal adenocarcinoma (EAD) benefits from a large improvement in five-year survival when detected in early stages, therefore, early detection strategies are paramount to mitigating disease. Those diagnosed with Barrett’s Esophagus (BE) are at higher risk for EAD, though there exists no routine s...
ORGANISM(S): Homo sapiens 
2025-12-08 | GSE271389 | GEO
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