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ProteomicsA heme-binding domain in a voltage gated porassium channel
Heme-affinity pull-down assays and proteomics of lysates from primary cortical neurons identified and EAG channel, hERG3 (Kv11.3) binds to heme.
ORGANISM(S): Mus musculus (Mouse) 
2020-09-17 | PXD019887 | Pride
Eag channel Ether-a-go-go Heme Waters q-tof Domain 
UnknownThe structural mechanism of KCNH-channel regulation by the eag domain.
Not available
S-EPMC3910112 | biostudies-literature
UnknownThe eag domain regulates hERG channel inactivation gating via a direct interaction.
Not available
S-EPMC3557309 | biostudies-literature
UnknownChlorpromazine binding to the PAS domains uncovers the effect of ligand modulation on EAG channel activity.
Not available
S-EPMC7105296 | biostudies-literature
UnknownHERG potassium channel regulation by the N-terminal eag domain.
Not available
S-EPMC4793660 | biostudies-literature
UnknownIdentification of undecylenic acid as EAG channel inhibitor using surface plasmon resonance-based screen of KCNH channels.
Not available
S-EPMC6637479 | biostudies-literature
GenomicsELK1 ChIP-seq
Chromatin immunoprecipitation of ELK1 in MCF10A cells detected by SOLiD sequencing
ORGANISM(S): Homo sapiens 
2012-08-20 | E-MTAB-830 | biostudies-arrayexpress
UnknownVoltage-sensor movements in the Eag Kv channel under an applied electric field.
Not available
S-EPMC9674223 | biostudies-literature
UnknownTuning of EAG K(+) channel inactivation: molecular determinants of amplification by mutations and a small molecule.
Not available
S-EPMC3434097 | biostudies-literature
UnknownThe Eag domain regulates the voltage-dependent inactivation of rat Eag1 K+ channels.
Not available
S-EPMC4204861 | biostudies-literature
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