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Aberrant protease activity has been implicated in the etiology of various prevalent diseases including neurodegeneration and cancer, in particular metastasis. Matrix-assisted laser desorption/ionization (MALDI) mass spectrometry imaging (MSI) has recently been established as a key technology for bio...
ORGANISM(S): Bos Taurus (ncbitaxon:9913) Mus Musculus (ncbitaxon:10090) 
AP2 transcription factors play important roles in development and cancer, we tried to clarify the role of the so far uncharacterised TFAP2E in colorectal cancer. We used GENE ST 1.0 Arrays to detail up and downregulated target genes of this AP-2 transcription factor. We used the ptarget mammalian ex...
ORGANISM(S): Homo sapiens 
Immunotherapy has opened hitherto unknown possibilities to treat cancer. Whereas some cancer types (e.g. melanoma) can be efficiently treated, others lack measurable positive effects (e.g. PDAC). Moreover, stratification of responders/non-responders is only possible in some cancer types (e.g. melano...
ORGANISM(S): Mus musculus (Mouse) 
2021-03-03 | PXD017236 | Pride
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