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TranscriptomicsDrosophila Ecdysone Receptor Study
We used the DamID method to systematically identify the binding sites of Ecdysone Receptor and its heterodimeric partner USP across the whole genome in Drosophila Kc cells. We find that the EcR sites are a subset of the USP sites and that only a proportion are ecdysone regulated from an accompanying...
ORGANISM(S): Drosophila melanogaster 
2008-05-01 | E-GEOD-9156 | biostudies-arrayexpress
ProteomicsGlobal quantitative proteomics reveals novel factors in the ecdysone signaling pathway in Drosophila melanogaster.
Global quantitative proteomics reveals novel factors in the ecdysone signaling pathway in Drosophila melanogaster.
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2015-01-23 | PXD001455 | Pride
Q exactive Ecdysone signaling Silac Drosophila melanogaster 
TranscriptomicsEcdysone Response Timecourse in Kc Cells
Kc167 Cells were plated at 0.5x106/ml and grown at 23.50C. They were treated with 20-HE (Sigma) at a final concentration of 5x10-7M. The reference sample was total RNA isolated at 0 hr. after treatment. The experimental samples were total RNA isolated from cells treated for 1, 3, 6, 12, 24, and 48 h...
ORGANISM(S): Drosophila melanogaster 
2008-06-12 | E-GEOD-11625 | biostudies-arrayexpress
TranscriptomicsEcdysone signaling and transcript signature in Drosophila cells resistant against methoxyfenozide
Methoxyfenozide (RH-2485) represents the group of non-steroidal ecdysteroid agonists with a dibenzoylhydrazine structure, that are used as novel biorational insecticides in the control of insect pests. Here we report on the selection of Drosophila melanogaster S2 cells for resistance to inhibition o...
ORGANISM(S): Drosophila melanogaster 
2010-11-08 | E-GEOD-17748 | biostudies-arrayexpress
TranscriptomicsEcdysone and Mediator trigger a metabolic switch uncoupling cell cycle from cell growth to end proliferation in Drosophila neural stem cells
Stem cells are highly abundant and proliferate rapidly during early development but become a rare population in most adult organs. The molecular mechanisms causing stem cells to exit proliferation at a specific time are not well understood. Here, we show that changes in energy metabolism induced by ...
ORGANISM(S): Drosophila melanogaster 
2014-08-14 | E-GEOD-53265 | biostudies-arrayexpress
TranscriptomicsEcR mutant midgut comparison
Comparisons between EcR mutant midgut and a reference control sample from mixed-stage normal midgut Keywords = Drosophila, ecdysone, network, genomic, microarray, organogenesis, EcR, midgut, central nervous system, salivary gland, epidermis, imaginal disc, development
ORGANISM(S): Drosophila melanogaster 
2010-06-05 | E-GEOD-540 | biostudies-arrayexpress
Transcriptomicssage gene RNAi experiment
Comparisons between the salivary glands upon the RNAi of sage gene vs. the control. Keywords = Drosophila, ecdysone, network, genomic, microarray, organogenesis, EcR, midgut, central nervous system, salivary gland, epidermis, imaginal disc, development
ORGANISM(S): Drosophila melanogaster 
2010-06-05 | E-GEOD-283 | biostudies-arrayexpress
Transcriptomics18h before puparium formation vs. puparium formation tissue comparisons
Samples at 18h before puparium formation were compared to samples at puparium formation for each the following tissues: epidermis with attached muscle, salivary gland, wing disc, midgut, and central nervous system. Keywords = Drosophila, ecdysone, network, genomic, microarray, organogenesis, EcR, mi...
ORGANISM(S): Drosophila melanogaster 
2010-06-05 | E-GEOD-542 | biostudies-arrayexpress
MetabolomicsUridine Attenuates Osteoclastogenesis and Ovariectomy Induced Bone Loss by Modulating the PI3K/Akt–FoxO ROS Signaling Axis

Osteoporosis is a metabolic bone disorder characterized by aberrant osteoclast activation, leading 

to excessive bone resorption and microarchitectural deterioration. Although the interconnection 

between osteoclast differentiation and cellular energy metabolism has been inc...

2026-04-09 | MTBLS13394 | MetaboLights
UnknownInsulin signaling pathways in lepidopteran ecdysone secretion.
Not available
S-EPMC3913887 | biostudies-literature
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