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ProteomicsDeciphering Mutational Effects on Inducible Nitric Oxide Synthase Conformational Dynamics via Quantitative Cross-Linking Mass Spectrometry and AlphaFold2 Subsampling
In this project, we compare the abundancies of cross-links in wild type and mutant iNOSoxyFMN-CaM complexes at specific interdomain interacting site and map the identified sites onto top AlphaFold 2 models for better understanding of iNOS protein dynamics.
ORGANISM(S): Homo sapiens (Human) 
2025-10-30 | PXD064795 | Pride
Nos Targeted Cross-linking mass spectrometry 
ProteomicsMolecular details of ligand binding to the intrinsically disordered N terminus of the neuropeptide Y receptor
Neuropeptide Y (NPY) receptors comprise a family of rhodopsin-like G-protein coupled receptors (GPCRs) that participate in controlling food intake, memory retention, and circadian rhythm, making them highly attractive drug targets. However, the multiligand nature of NPY receptors, such as the NPY re...
ORGANISM(S): Homo Sapiens Escherichia Coli Sus Scrofa 
2026-03-24 | PXD051865 | panorama
ProteomicsAnalysis of N-Glycosylation for SARS-CoV-2 expressed receptor-binding domain VOCs and membrane protein with LC-MS.
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can infect human cells by first attaching to the ACE-2 receptor via its receptor-binding domain (RBD) in the spike protein. We investigated the influence of N-glycosylation sites of the RBD and the membrane (M) protein on IgG antibody bind...
ORGANISM(S): Severe Acute Respiratory Syndrome Coronavirus 2 
PXD048930 | panorama
UnknownColombian surgical outcomes study insights on perioperative mortality rate, a main indicator of the lancet commission on global surgery - a prospective cohort study.
Not available
S-EPMC11382124 | biostudies-literature
UnknownSARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study.
Not available
S-EPMC7995808 | biostudies-literature
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