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TranscriptomicsSmoking and Obesity Related Molecular Alterations in Clear Cell Renal Cell Carcinoma
Both cigarette smoking and obesity have been implicated in increased risk of clear cell renal cell carcinoma (ccRCC); however, there are limited data regarding the molecular mechanisms that underlie these associations. We used a multi-stage design to identify and validate specific molecular targe...
ORGANISM(S): Homo sapiens 
2014-01-10 | E-GEOD-46699 | biostudies-arrayexpress
UnknownGenomic analysis reveals that immune function genes are strongly linked to clinical outcome in the North Central Cancer Treatment Group n9831 Adjuvant Trastuzumab Trial.
Not available
S-EPMC4334774 | biostudies-literature
TranscriptomicsDeep Sequence Analysis of the Relationship between Gene Expression, CpG Island Methylation, and Gene Copy Number in Breast Cancer Cells
We used deep sequencinge technology to profile the transcriptome, gene copy number, and CpG island methylation status simultaneously in eight commonly used breast cell lines to develop a model for how these genomic features are integrated in estrogen receptor positive (ER+) and negative breast cance...
ORGANISM(S): Homo sapiens 
2011-03-16 | E-GEOD-27003 | biostudies-arrayexpress
TranscriptomicsExpression Profiling of Formalin-Fixed Parafin-Embedded Primary Breast Tumors DASL Cancer Panel
HER2-positive and HER2-negative samples are compared within this DASL Cancer Panel Platform Two-class comparison
ORGANISM(S): Homo sapiens 
2010-12-20 | E-GEOD-25231 | biostudies-arrayexpress
TranscriptomicsExpression Profiling of Formalin-Fixed Parafin-Embedded Primary Breast Tumors Whole Genome DASL
HER2-positive and HER2-negative samples are compared within this Whole Genome Platform Two-class comparison
ORGANISM(S): Homo sapiens 
2010-12-20 | E-GEOD-25233 | biostudies-arrayexpress
TranscriptomicsAn Integrated Model of the Transcriptome Landscape of HER2-Positive Breast Cancer
The goal of our study is to build an integrated transcriptome landscape model for HER2 positive breast tumors and identify the crucial signaling pathways associated with HER2 tumors. Genomic features include, 685 genes that were differentially expressed only in HER2-positive tumors, 102 genes that w...
ORGANISM(S): Homo sapiens 
2013-12-06 | E-GEOD-45419 | biostudies-arrayexpress
GenomicsGlioma GWAS summary statistics DAC
Data Access Committee EGAC00001001116
EGAC00001001116 | EGA
GenomicsGlioma GWAS summary statistics
Meta-analysis association statistics from case-control analysis (includes imputed SNPs)
EGAD00010001657 | EGA
GenomicsSummary statistics from genome-wide association study in glioma of 12,488 cases and 18,169 controls.
Genome-wide association studies (GWAS) have transformed our understanding of glioma susceptibility, but individual studies have had limited power to identify risk loci. We performed a meta-analysis of existing GWAS and two new GWAS, which totaled 12,488 cases and 18,169 controls. We identified five ...
EGAS00001003372 | EGA
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