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MetabolomicsMulti-Omics Approach to Elucidate Cerebrospinal Fluid Changes in Dogs with Intervertebral Disc Herniation
Herniation of the intervertebral disc (IVDH) is the most common cause of neurological and intervertebral disc degeneration-related diseases. Since the disc starts to degenerate before it can be observed by currently available diagnostic methods, there is an urgent need for novel diagnostic approache...
2021-11-04 | MTBLS2689 | MetaboLights
ProteomicsLC-MS/MS Data of Skeletal Muscle and Plasma of Preruminant Calves fed with Leucine and Threonine Supplemented Diets
The objective of present work is to use foodomics approaches in calves’ skeletal muscle and plasma to fully assess the effects of the supplementations of leucine and threonine in the MR during preweaning period (5.6 days to 53.6 days) under the hypothesis that AA supplementation will modify the ener...
ORGANISM(S): Bos taurus (Bovine) 
2020-02-17 | PXD016098 | Pride
Tmt Amino acid  calf  leucine  threonine  muscle  plasma  proteomics Lc-ms/ms 
ProteomicsDDA-MS serum proteomics in dogs with leishmaniosis
Serum proteomes of healthy and Leishmania-infected dogs were analyzed by DDA-MS approach to generate sample-specific spectral library for subsequent SWATH-MS analysis, namely pooled, mixed control, mixed case (Leishmania-infected), ProteoMiner enriched, and 3 SCX fractions; all containing iRT pepti...
ORGANISM(S): Canis familiaris (Dog) (Canis lupus familiaris) 
2023-05-10 | PXD039763 | Pride
Canine Proteomics Serum Leishmania infantum Dda 
ProteomicsDIA-MS serum proteomics in dogs with leishmaniosis
Serum proteomes of healthy and Leishmania-infected dogs were analyzed by DIA-MS approach using non-depleted serum and 60 min gradient time in order to study host response to infection.
ORGANISM(S): Canis familiaris (Dog) (Canis lupus familiaris) 
2023-05-10 | PXD039765 | Pride
Canine Proteomics Dia Serum Leishmania infantum 
ProteomicsCanine pyometra - plasma proteomics
Canine pyometra is a common inflammatory disease of the uterus in sexually mature bitches, caused by a secondary bacterial infection which leads to change in the plasma protein associated with the innate immune system. Proteomic offers a means to determine the profile of plasma in dogs with pyometr...
ORGANISM(S): Canis familiaris (Dog) (Canis lupus familiaris) 
2020-05-18 | PXD015951 | Pride
Proteomics Tmt Serum Pyometra Dog 
ProteomicsSerum proteomics in cats with cardiomyopathy and congestive heart failure
In this study, we aimed to identify novel serum biomarkers in feline primary cardiomyopathies with congestive heart failure, which can help to understand disease pathogenesis and assist the disease diagnosis, prognosis and management. The study included 15 cats diagnosed with CHF and CM, 5 cats with...
ORGANISM(S): Felis catus (Cat) (Felis silvestris catus) 
2020-07-19 | PXD017761 | Pride
Congestive heart failure Cat Cardiomyopathy Tmt-based proteomics Lc-ms/ms 
ProteomicsQuantitative label-based canine faecal proteomics
In small animals, diarrhoea is a regular presentation, the aetiology of which can be varied, from an isolated self-limiting event to more serious episodes requiring symptomatic and supportive treatment. Chronic diarrhoea, defined as diarrhoea lasting longer than 3 weeks, is a relatively common probl...
ORGANISM(S): Canis lupus 
2022-08-29 | PXD017454 | Pride
Faecal proteomics Dog Chronic diarrhoea Tandem mass tags 
ProteomicsTMT-based proteomics of longissimus lumborum muscle in newly weaned piglets after dietary Spirulina inclusion and enzyme supplementation
The objective of this study was to evaluate the impact of dietary Spirulina and lysozyme supplementation over the muscle proteome of piglets during the post-weaning stage. Thirty piglets were randomly distributed among three diets: control (no microalga), SP (10% Spirulina) and SP+L (10% Spirulina +...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2021-05-24 | PXD024083 | Pride
Spirulina Weaned piglet Muscle proteome Tandem mass tag Cazyme 
ProteomicsSerum proteome profiling in canine chronic valve disease using TMT-based quantitative proteomics
Cardiovascular-related disorders (CVD) account for the highest mortality rates in the world, and affect the quality and the quantity of life of patients, creating an economic burden of prolonged therapeutic intervention. The aim of this study was to evaluate the serum protein profile of healthy and ...
ORGANISM(S): Canis familiaris (Dog) (Canis lupus familiaris) 
2020-05-26 | PXD017129 | Pride
Dog Tandem mass tag Chronic valve disease Serum proteomics 
ProteomicsTMT-based proteomic analysis of CSF in dogs with intervertebral disc herniation
In our study, MS-based high-resolution proteomic analysis of CSF have been employed in order to gain deeper insights into changes occurring during IVDH in dogs, monitoring the pathophysiological processes at the protein and metabolite levels. The proteomics study involved canine patients classified ...
ORGANISM(S): Canis familiaris (Dog) (Canis lupus familiaris) 
2021-11-25 | PXD024921 | Pride
Proteomics Intervertebral disc herniation Tmt Csf Dog 
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