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Given the tendency to substitute cellular vaccines with acellular ones, and the complete lack of virulence shown by the C. albicans cell wall mutant ecm33∆, we performed the characterization of its EVs and test their possible use as vaccine for invasive candidiasis. Label free proteomics was carried...
ORGANISM(S): Candida albicans (Yeast) 
2025-05-07 | PXD055891 | Pride
Prp45 is a budding yeast NineTeen-Complex associated factor, which plays a role in pre-mRNA splicing. In addition to its documented involvement in the second step of splicing, here we show that it is important in the early stages of co-transcriptional spliceosome assembly as well. To determine the o...
ORGANISM(S): Saccharomyces cerevisiae 
The fungal pathogen Candida albicans produces dark-pigmented melanin when grown in a basal medium containing 1 mM l-DOPA as melanin substrate. In the widely used C. albicans strain SC5314, melanin appeared after 3-4 days of incubation in l-DOPA medium. The experiment was designed to reveal cadidat...
ORGANISM(S): Candida albicans 
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