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Assess the full impact of estrogen receptor beta on transcription by a full transcriptome analysis of ERa and ERb-mediated gene regulation in T47D breast cancer cell line with TET-OFF regulated ERb expression.
ORGANISM(S): Homo sapiens 
Assess the full impact of estrogen receptor beta on transcription by a full transcriptome analysis of ERb-mediated gene regulation in the two colon cancer cell lines HCT116 and HT29. The colon cancer cell lines do not express endogenous ER but is made ERb-expressing by lentiviral transduction of an ...
ORGANISM(S): Homo sapiens 
Control experiment to confirm ligand independent effect on gene regulation by ERb in HT29 cells. The colon cancer cell lines do not express endogenous ER but is made ERb-expressing by lentiviral transduction of an ERb expression cassette. Introduction of ERb makes it possible to study the role and f...
ORGANISM(S): Homo sapiens 
Assess the full impact of estrogen receptor beta on transcription by a full transcriptome analysis of ERb-mediated gene regulation in the SW480 colon cancer cell line. The colon cancer cell line SW480 does not express endogenous ER but is made ERb-expressing by lentiviral transduction of an ERb exp...
ORGANISM(S): Homo sapiens 
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