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TranscriptomicsLinking toxicant physiological mode of action with induced gene expression changes in Caenorhabditis elegans: fluoranthene
Physiologically based modelling using DEBtox (dynamic energy budget in toxicology) and transcriptional profiling were used in Caenorhabditis elegans to identify how physiological modes of action, as indicated by effects on system level resource allocation were associated with changes in gene express...
ORGANISM(S): Caenorhabditis elegans 
2010-05-05 | E-GEOD-21011 | biostudies-arrayexpress
MetabolomicsA metabolic dependency of EBV can be targeted to hinder B cell transformation

Following infection of B cells, Epstein Barr virus (EBV) engages host pathways that mediate cell proliferation and transformation, contributing to the propensity of the virus to drive immune dysregulation and lymphomagenesis. We found that the EBV protein EBNA2 initiates NAD de novo bios...

2024-04-29 | MTBLS2243 | MetaboLights
TranscriptomicsGenome-wide analysis of adult adrenocortical cells gene expression after 48 h ACTH treatment
Analysis of ACTH-regulation on adrenocortical cells at gene expression level. The hypothesis tested in the present study was that ACTH increases chronic cell growth and steroidogenesis in adrenal glands by changing the gene expression profile. Results provide important information of the response of...
ORGANISM(S): Homo sapiens 
2010-07-08 | E-GEOD-20669 | biostudies-arrayexpress
TranscriptomicsTranscriptional plasticity of a soil arthropod across different ecological conditions
It has long been recognized that species occupy a specific ecological niche within their ecosystem. The ecological niche is defined as the number of conditions and resources that limit species distribution. Within their ecological niche, species do not exist in a single physiological state but in a ...
ORGANISM(S): Folsomia candida 
2011-02-15 | E-GEOD-21213 | biostudies-arrayexpress
TranscriptomicsLinking toxicant physiological mode of action with induced gene expression changes in Caenorhabditis elegans: atrazine
Physiologically based modelling using DEBtox (dynamic energy budget in toxicology) and transcriptional profiling were used in Caenorhabditis elegans to identify how physiological modes of action, as indicated by effects on system level resource allocation were associated with changes in gene express...
ORGANISM(S): Caenorhabditis elegans 
2010-03-23 | E-GEOD-21008 | biostudies-arrayexpress
TranscriptomicsLinking toxicant physiological mode of action with induced gene expression changes in Caenorhabditis elegans: cadmium
Physiologically based modelling using DEBtox (dynamic energy budget in toxicology) and transcriptional profiling were used in Caenorhabditis elegans to identify how physiological modes of action, as indicated by effects on system level resource allocation were associated with changes in gene express...
ORGANISM(S): Caenorhabditis elegans 
2010-05-05 | E-GEOD-21010 | biostudies-arrayexpress
TranscriptomicsGenome-wide analysis of fetal adrenocortical cells gene expression after 48 h ACTH treatment
Analysis of ACTH-regulation on adrenocortical cells at gene expression level. The hypothesis tested in the present study was that ACTH increases chronic cell growth and steroidogenesis in adrenal glands by changing the gene expression profile. Results provide important information on the changes of ...
ORGANISM(S): Homo sapiens 
2010-07-08 | E-GEOD-20675 | biostudies-arrayexpress
TranscriptomicsGenome-wide analysis of adrenocortical cells gene expression after 48 h ACTH treatment
This SuperSeries is composed of the following subset Series: GSE20669: Genome-wide analysis of adult adrenocorical cells gene expression after 48 h ACTH treatment GSE20675: Genome-wide analysis of fetal adrenocorical cells gene expression after 48 h ACTH treatment Refer to individual Series
ORGANISM(S): Homo sapiens 
2010-06-16 | E-GEOD-20676 | biostudies-arrayexpress
TranscriptomicsFunctional environmental genomics of a municipal landfill soil
We investigated the toxicity of soil samples derived from a former municipal landfill site in the South of the Netherlands, where a bioremediation project is running aiming at reusing the site for recreation. Both an organic soil extract and the original soil sample was investigated using the ISO st...
ORGANISM(S): Folsomia candida 
2012-04-15 | E-GEOD-37154 | biostudies-arrayexpress
UnknownRibosome clearance by FusB-type proteins mediates resistance to the antibiotic fusidic acid.
Not available
S-EPMC3277530 | biostudies-literature
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