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ProteomicsCharacterization of the diphthamide modification of eEF2 in Arabidopsis thaliana
Diphthamide, a post-translationally modified histidine residue of eukaryotic TRANSLATION ELONGATION FACTOR2 (eEF2), is the human host cell-sensitizing target of diphtheria toxin. Diphthamide biosynthesis depends on the 4Fe-4S-cluster protein Dph1 catalyzing the first committed step, as well as Dph2 ...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2022-08-11 | PXD034873 | Pride
Diphthamide translation elongation factor 2 (eef2) arabidopsis thaliana growth development 
Proteomics(LCMS)/MS studies of prefrontal cortex synaptosomal fractions in Eef2 HET mice - eEF2 in the prefrontal cortex regulates excitatory synaptic transmission and social novelty behavior.
To investigate the protein expression changes at the synapse induced by Eef2 reduction, we performed (LCMS)/MS-based proteomic analysis in crude synaptosome preparations from the PFC of WT and Eef2 HET mice.
ORGANISM(S): Mus musculus (Mouse) 
2022-08-15 | PXD034864 | Pride
Prefrontal cortex (lcms)/ms Synaptosome Eef2 
GenomicsRole of eEF2 diphthamide modification in translational fidelity
Role of eEF2 diphthamide modification in translational fidelity
PRJNA735209 | ENA
UnknownThe channel-kinase TRPM7 regulates phosphorylation of the translational factor eEF2 via eEF2-k.
Not available
S-EPMC3038675 | biostudies-literature
UnknownCoordination of changes in expression and phosphorylation of eukaryotic elongation factor 2 (eEF2) and eEF2 kinase in hypertrophied cardiomyocytes.
Not available
S-EPMC5613342 | biostudies-literature
GenomicsCrosstalk between eIF2α and eEF2 phosphorylation pathways optimizes translational arrest in response to oxidative stress
Crosstalk between eIF2α and eEF2 phosphorylation pathways optimizes translational arrest in response to oxidative stress
PRJNA565395 | ENA
Genomics
Rip-seq of eEF2 in ESCC
PRJNA875230 | ENA
GenomicsDiphthamide modification of eEF2 is required for gut tumor-like hyperplasia induced by oncogenic Ras
Diphthamide modification of eEF2 is required for gut tumor-like hyperplasia induced by oncogenic Ras
PRJNA592564 | ENA
TranscriptomicsCrosstalk between eIF2α and eEF2 phosphorylation pathways optimizes translational arrest in response to oxidative stress
The cellular stress response triggers a cascade of events leading to transcriptional reprogramming and a transient inhibition of global protein synthesis, which is thought to be mediated by phosphorylation of eukaryotic initiation factor-2α (eIF2α). Using mouse embryonic fibroblasts (MEFs) and the f...
ORGANISM(S): Mus musculus 
2019-09-14 | GSE137409 | GEO
UnknownFAM86A methylation of eEF2 links mRNA translation elongation to tumorigenesis.
Not available
S-EPMC11069438 | biostudies-literature
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