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ProteomicsDetection of Eepd1 myristoylation in vivo by data-independent acquisition mass spectrometry (DIA-MS)
Eight 8-week-old male C57BL/6J mice were injected with adenovirus expressing Eepd1-Flag (3×10^8/mouse) into multiple sites in their iWAT. Three days later, each mouse was administered 50 mg/kg of myristic acid solution (prepared in 0.1% BSA) via oral gavage. Half of the mice were then exposed to 8°C...
ORGANISM(S): Mus musculus (Mouse) 
2024-12-23 | PXD058559 | Pride
Iwat Mouse Dia-ms Myristoylation Eepd1 
UnknownEEPD1 regulates inflammation and endothelial apoptosis in atherosclerosis through KLF4-EEPD1-ERK axis.
Not available
S-EPMC12017893 | biostudies-literature
GenomicsMyristoylated Eepd1 Enhances Lipolysis and Thermogenesis through PKA Activation to Combat Obesity
Myristoylated Eepd1 Enhances Lipolysis and Thermogenesis through PKA Activation to Combat Obesity
PRJNA1195567 | ENA
TranscriptomicsMyristoylated Eepd1 Enhances Lipolysis and Thermogenesis through PKA Activation to Combat Obesity
Middle-aged obesity, characterized by excessive fat accumulation and systemic energy imbalance, often precedes various health complications. Recent research has unveiled a surprising link between DNA damage response and energy metabolism. Here, we explore the role of Eepd1, a DNA repair enzyme, in r...
ORGANISM(S): Mus musculus 
2025-01-01 | GSE283770 | GEO
UnknownEEPD1 promotes repair of oxidatively-stressed replication forks.
Not available
S-EPMC9846428 | biostudies-literature
UnknownMyristoylated Eepd1 Enhances Lipolysis and Thermogenesis through PKA Activation to Combat Obesity.
Not available
S-EPMC11733280 | biostudies-literature
UnknownDistinct roles of structure-specific endonucleases EEPD1 and Metnase in replication stress responses.
Not available
S-EPMC7380491 | biostudies-literature
UnknownThe endonuclease EEPD1 mediates synthetic lethality in RAD52-depleted BRCA1 mutant breast cancer cells.
Not available
S-EPMC5693420 | biostudies-literature
UnknownEEPD1 attenuates radiation-induced cardiac hypertrophy and apoptosis by degrading FOXO3A in cardiomyocytes.
Not available
S-EPMC11659772 | biostudies-literature
UnknownObstructive Sleep Apnea Syndrome Exacerbates NASH Progression via Selective Autophagy-Mediated Eepd1 Degradation.
Not available
S-EPMC11425227 | biostudies-literature
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