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EF-P dependent genes in Salmonella Typhimurium
Elongation factor P (EF-P) is required to enhance peptidyl transferase on pausing ribosomes, which can be induced by certain codons on mRNA. It regulates expression of genes in specific conditions. Therefore, to search EF-P mediated ribosome stalling motif, ribosome profiling has been used on organi...
ORGANISM(S): Salmonella enterica subsp. enterica serovar Typhimurium str. 14028S 
2024-07-01 | GSE249725 | GEO
Protein synthesis is performed by the ribosome and a host of highly conserved elongation factors. Elongation factor P (EF-P) prevents ribosome stalling at difficult-to-translate sequences, particularly polyproline tracts. In bacteria, phenotypes associated with efp deletion range from modest to leth...
ORGANISM(S): Bacillus subtilis subsp. subtilis str. 168 
2024-03-06 | GSE249203 | GEO
YfmR is a translation factor that prevents ribosome stalling and cell death in the absence of EF-P
Translation elongation factor P (EF-P) alleviates ribosome pausing at a subset of motifs encoding consecutive proline residues and is required for growth in many organisms. Here we show that Bacillus subtilis EF-P also alleviated ribosome pausing at sequences encoding tandem prolines, and ribosomes ...
ORGANISM(S): Bacillus subtilis 
2019-05-20 | GSE126234 | GEO
Translation elongation factor P (EF-P) alleviates ribosome pausing at a subset of motifs encoding consecutive proline residues and is required for growth in many organisms. Here we show that Bacillus subtilis EF-P also alleviated ribosome pausing at sequences encoding tandem prolines, and ribosomes ...
ORGANISM(S): Bacillus subtilis 
2019-05-20 | GSE126233 | GEO
Suppressor mutations in ribosomal proteins and FliY restore Bacillus subtilis swarming motility in the absence of EF-P [Ribosome Profiling]
Suppressor mutations in ribosomal proteins and FliY restore Bacillus subtilis swarming motility in the absence of EF-P [RNA sequencing]
Bacterial translational elongation factor P (EF-P) is required during translation of proteins containing consecutive proline motifs. Several transcription and translational regulators contain polyproline motifs and therefore, EF-P might also affect levels of proteins that do not contain polyproline ...
ORGANISM(S): Corynebacterium glutamicum ATCC 13032 
2020-04-06 | PXD014742 | Pride
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