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TranscriptomicsDEPTOR cell-autonomously promotes adipogenesis and associates with obesity
An understanding of the mechanisms regulating white adipose tissue (WAT) formation is key for developing of new tools to treat obesity and its related diseases. Here, we identify DEPTOR as a positive regulator of adipogenesis whose expression is associated with obesity. In a polygenic mouse model of...
ORGANISM(S): Mus musculus 
2012-08-14 | E-GEOD-38321 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of cell lines produced from premalignant tumors with induced sensence
Oncogene-induced senescence is a cellular response that may be crucial for protection against cancer development, but its investigation has so far been restricted to cultured cells that have been manipulated to overexpress an oncogene. Here we analyse tumours initiated by an endogenous oncogene, ras...
ORGANISM(S): Homo sapiens 
2007-10-02 | E-GEOD-2487 | biostudies-arrayexpress
GenomicsRecurrent mTORC1-activating RRAGC mutations in follicular lymphoma
Follicular lymphoma (FL) is an incurable B-cell malignancy characterized by the t(14;18) and mutations in one or more components of the epigenome. Whilst frequent gene mutations in signaling pathways, including JAK-STAT, NOTCH and NF-κB, have also been defined, the spectrum of these mutations typic...
EGAS00001001190 | EGA
Genomicsena-DATASET-BCI-18-03-2015-12:48:54:303-380 - samples
Whole exome sequencing data of 5 patients diagnosed with FL that had undergone several relapse episodes without evidence of transformation
EGAD00001001301 | EGA
GenomicsBarts Cancer Institute - Follicular Lymphoma Whole Genome Sequencing Project Data Access Committee
Data Access Committee EGAC00001000086
EGAC00001000086 | EGA
UnknownLack of p38 activation in T cells increases IL-35 and protects against obesity by promoting thermogenesis
Not available
S-SCDT-10_1038-S44319-024-00149-Y | biostudies-other
UnknownOMA1 protects from liver injury and tumorigenesis during aging by controlling hepatic immunogenicity
Not available
S-SCDT-10_1038-S44318-026-00839-4 | biostudies-other
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