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ProteomicsProteomics of NGF-TrkA signaling dynamics in neuroblastoma cells
We used quantitative mass spectrometry-based proteomics to unravel global nerve growth factor (NGF)-induced TrkA signaling dynamics at the interactome, phosphoproteome and proteome level. A tetracycline-inducible system for TrkA expression was generated in the human neuroblastoma cell line, SH-SY5Y....
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-31 | MSV000080834 | MassIVE
TranscriptomicsBone morphogenetic protein-7 is a MYC target with pro-survival functions in childhood medulloblastoma
Medulloblastoma (MB) is the most common malignant brain tumor in children, among whom overexpression or amplification of MYC oncogenes has been associated with poor clinical outcome. Although the MYC functions during normal development and oncogenesis in various systems have been extensively investi...
ORGANISM(S): Homo sapiens 
2011-05-16 | E-GEOD-22139 | biostudies-arrayexpress
UnknownHigh-Dose Chemotherapy and Blood Autologous Stem-Cell Rescue Compared With Standard Chemotherapy in Localized High-Risk Ewing Sarcoma: Results of Euro-E.W.I.N.G.99 and Ewing-2008.
Not available
S-EPMC6209090 | biostudies-literature
UnknownXIAP represents a promising therapeutic target for relapsed/refractory ALL
Not available
S-SCDT-10_15252-EMMM_202114557 | biostudies-other
GenomicsGenomes of Relapsing Neuroblastoma
Neuroblastoma is a malignancy of the developing sympathetic nervous system that is often lethal when relapse occurs, but the molecular mechanisms behind this process are poorly defined. We here used whole-exome sequencing, mRNA expression, array CGH and DNA methylation analysis to holistically chara...
EGAS00001001387 | EGA
GenomicsTelomerase activation by genomic rearrangements in high-risk neuroblastoma
Neuroblastoma is a malignant pediatric tumor of the sympathetic nervous system1. Roughly half of these tumors regress spontaneously or are cured by limited therapy. By contrast, high-risk neuroblastomas have an unfavorable clinical course despite intensive multimodal treatment, and their molecular b...
EGAS00001001308 | EGA
Genomicsena-DATASET-UKEssen-09-09-2015-10:54:33:815-144 - samples
In this dataset, 16 trios- primary tumor, relapse and corresponding normals- for patients with neuroblastoma are provided. For one patient, more than one relapse was available for the analyses.
EGAD00001001607 | EGA
GenomicsRelapsed and Primary Neuroblastoma DAC
Data Access Committee EGAC00001000373
EGAC00001000373 | EGA
ProteomicsTherapeutic targeting of ATR in alveolar rhabdomyosarcoma
Despite advances in multi-modal treatment approaches, clinical outcomes of patients suffering from PAX3-FOXO1 fusion oncogene-expressing alveolar rhabdomyosarcoma (ARMS) remain dismal. Here we show that PAX3-FOXO1-expressing ARMS cells are sensitive to pharmacological ataxia telangiectasia and Rad3 ...
ORGANISM(S): Homo Sapiens (human) 
2022-07-11 | PXD035131 | JPOST Repository
Genomicsena-DATASET-UCL-ICH-25-11-2015-12:32:35:398-26 - samples
Description not provided
EGAD00001001687 | EGA
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