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ProteomicsTranslation rescue by targeting Ppp1r15a upstream open reading frame in vivo
The eIF2 initiation complex is central to maintaining a functional translation machinery. Extreme stress such as life-threatening sepsis exposes vulnerabilities in this tightly regulated system, resulting in an imbalance between the opposing actions of kinases and phosphatases on the main regulatory...
ORGANISM(S): Mus musculus (Mouse) Homo sapiens (Human) 
2022-09-28 | PXD030889 | Pride
Lcmsmsi Phoshporylation Ppp1r15a Uorf Kidney Eif2 initation complex Translation 
ProteomicsPhosphoproteome of a patient-matched cell line model of colon cancer metastasis
The contributions of phosphorylation-mediated signaling networks to colon cancer metastasis are poorly defined. To better understand the role of constitutive signaling alterations in cancer progression, the global phosphoproteomes of the SW480 and SW620 cell lines were compared by LC-MS/MS. These pa...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-04-01 | MSV000080864 | MassIVE
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