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KSHV requires eIF3d for cholesterol biosynthesis
eIF3d controls the persistent integrated stress response
In current study, we developed a molecular affinity strategy based on the Tudor domain of SMN, a naturally occurring methylarginine reader protein, for comprehensive proteomic profiling of cellular arginine methylation. We demonstrated that the Tudor domain-based approach exhibits broad specificity ...
ORGANISM(S): Homo sapiens (Human) 
2025-12-15 | PXD053390 | Pride
eIF4E-independent translation is largely eIF3d-dependent
A phosphorylation-regulated eIF3d translation switch mediates cellular adaptation to metabolic stress
All cells respond to intrinsic and extrinsic stresses by reducing global protein synthesis and activating select gene programs necessary for survival. Here, we show the fundamental integrated stress response (ISR) is driven by the non-canonical cap-binding protein eIF3d which acts as a master effect...
ORGANISM(S): Homo sapiens 
2023-09-11 | GSE236188 | GEO
EIF3D Safeguards the Homeostasis of Key Signaling Pathways in Human Primed Pluripotency [RNA-seq]
EIF3D Safeguards the Homeostasis of Key Signaling Pathways in Human Primed Pluripotency [Ribo-seq]
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