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TranscriptomicsThe immediate early gene product EGR1 and Polycomb Group proteins interact in epigenetic programming during chondrogenesis
Chondrogenic differentiation was induced in ATDC5 cells in the absence (RNAi) or presence of EGR1 (Early Growth Response Protein 1); RNA samples were collected at t=0, 2, 4.5, 8,16, 24, 72 hrs.
ORGANISM(S): Mus musculus 
2013-05-07 | E-MTAB-1464 | biostudies-arrayexpress
TranscriptomicsDifferences in gene expression profiles between human preimplantation embryos cultured in two different IVF culture media
Study question: Is gene expression in human preimplantation embryos affected by medium used for culturing embryos during an IVF treatment? Summary answer: Six days of in vitro culture of human preimplantation embryos resulted in a medium-dependent expression level of genes involved in apoptosis, pr...
ORGANISM(S): Homo sapiens 
2015-07-08 | E-MTAB-3405 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of lymphocytes from BRCA1-mutation carriers and controls in response to irradiation
Lymphocytes from 10 BRCA1-mutation carriers and 6 controls were cultured and irradiated with 10Gy. Additional 15 mutation carriers and 5 controls were subjected to the same treatment and scanned separately.
ORGANISM(S): Homo sapiens 
2018-10-31 | E-MTAB-982 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse liver response to a glucose challenge in healthy and insulin resistant C57BL/6J mice
The goal of this experiment is to compare the transcriptional response to a metabolic stressor (glucose bolus) between healthy and insulin resistant mouse liver. Mice with an isogenic background (C57BL/6J mice) were fed diets for 12 weeks containing either 10 or 45% fat by energy (mainly palm oil) a...
ORGANISM(S): Mus musculus 
2012-03-21 | E-MTAB-601 | biostudies-arrayexpress
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