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The β-amyloid precursor protein APP and the related APLPs, undergo complex proteolytic processing giving rise to several fragments. Whereas it is well established that Aβ accumulation is a central trigger for Alzheimer disease (AD), the physiological role of APP family members and their diverse pr...
ORGANISM(S): Mus musculus 
This set of 320 profiles was utilized to construct, validate and evaluate a gene-expression based classifier of outcome of neuroblastoma patients
ORGANISM(S): Homo sapiens 
Comprehensive in vitro expression profiling of small chemical compound inhibitors of TGFbR1 kinase activity. Additional file E-MTAB-265.additonal.1.zip contains excel file with Taqman data validating the array normalization method
ORGANISM(S): Homo sapiens 
The data set contains bam files aligned using bwa-0.7.8 mem -t 8 -R.
In order to identify critical changes in the genetic network of Rage signaling induced by TPA throughout a 48 h kinetic, global gene expression analysis was performed. Total RNA from untreated, 24h acetone- and 6, 12, 24, 48 h TPA-treated wt and Rage KO back skin was prepared (n=3 independent animal...
ORGANISM(S): Mus musculus 
Male rats from one of four strains (Wistar, AA, HAD or P) were housed individually in standard hanging rodent cages (Ehret, Emmendingen, Germany) on a 12-hour light-dark cycle with lights on at 07:00 a.m.. Animals were provided with food (Sniff, Soest, Germany), tap water, 5, 10 and 20% (v/v) ethano...
ORGANISM(S): Rattus norvegicus 
We sequenced two tumor/normal pairs obtained from two paediatric medulloblastoma patients (MB14 and MB24) with at least 30x coverage on all commonly used next-generation sequencing platforms for whole genome sequencing (SOLiD 4, 5500xl SOLiD, Illumina's HiSeq2000, and Complete Genomic' technology). ...
ORGANISM(S): Homo sapiens 
abundance based on Spectral counting, Gly and Lac substrate, Interaction consistency score: 6.5, Coverage: 21
ORGANISM(S): 511145 
2010-00-00 | 1076937984 | PAXDB
HSC73_clone: Bone marrow mononuclear cells from the healthy 73 years old female were thawed and labeled with Alexa-Fluor 488-conjugated anti-CD34 (581, Biolegend), Alexa-Fluor 700-conjugated anti-CD38 (HIT2, eBioscience), a cocktail of APC-conjugated lineage antibodies consisting of anti-CD4 (RPA-T4...
To investigate the immune response and mechanisms associated with severe COVID-19, we performed single-cell RNA-seq on nasopharyngeal and bronchial samples from 19 clinically well-characterized patients with moderate or critical disease and from 5 healthy controls. We identified airway epithelial ce...
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