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TranscriptomicsProtoanemonin: A new natural quorum sensing inhibitor that selectively activates iron starvation response
Many Gram-negative bacteria employ cell-to-cell communication mediated by N-acyl homoserine lactones (quorum sensing) to control expression of a wide range of genes including, but not limited to, genes encoding virulence factors. Outside the laboratory, the bacteria live in complex communities where...
ORGANISM(S): Pseudomonas aeruginosa 
2012-06-12 | E-GEOD-27674 | biostudies-arrayexpress
TranscriptomicsChIP-chip mapping of RNA polymerase II binding in D.melanogaster stage 5 embryos
ChIP-chip was performed using chromatin isolated from formaldehyde crosslinked, stage 5 embryos, and 8WG16 monoclonal antibody against RNA polymerase II(Covance Inc.). The chromatin immunoprecitation and hybridization for each antibody were carried out in duplicates, and in each chromatin immunopr...
ORGANISM(S): Drosophila melanogaster 
2011-02-28 | E-TABM-1130 | biostudies-arrayexpress
ProteomicsM.barkeri with/without hematite/PCA
Paper title: The reduction of environmentally abundant iron oxides by the methanogen Methanosarcina barkeri Author List: Efrat Eliani-Russak, Zohar Tik, Shaked Uzi-Gavrilov, Michael M. Meijler and Orit Sivan Citation: Front. Microbiol. 14:1197299. doi: 10.3389/fmicb.2023.1197299 Brief description of...
ORGANISM(S): Methanosarcina Barkeri (ncbitaxon:2208) 
2024-12-29 | MSV000096740 | MassIVE
Transcriptomicscardiomyocyte induced from fibroblast
the fibroblast from the skin of the mouse dorsum become the cardiomyocyte do a lot of experiment and gradually find out the best combination of the induction
ORGANISM(S): Mus musculus 
2014-10-02 | E-GEOD-32605 | biostudies-arrayexpress
GenomicsEstablishment of regions of genomic activity during the Drosophila maternal-to-zygotic transition
A conspicuous feature of early animal development is the lack of transcription from the embryonic genome, and it typically takes several hours to several days (depending on the species) until widespread transcription of the embryonic genome begins. Although this transition is ubiquitous, relatively ...
ORGANISM(S): Drosophila melanogaster 
2014-10-16 | E-GEOD-58935 | biostudies-arrayexpress
GenomicsZelda binding in the early Drosophila melanogaster embryo marks regions subsequently activated at the maternal-to-zygotic transition
The earliest stages of development in most metazoans are driven by maternally deposited proteins and mRNAs, with widespread transcriptional activation of the zygotic genome occurring hours after fertilization, at a period known as the maternal-to-zygotic transition (MZT). In Drosophila, the MZT is p...
ORGANISM(S): Drosophila melanogaster 
2011-07-18 | E-GEOD-30757 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of aging in the primate brain
An experiment was performed to study effects of aging on gene expression in chimpanzee brains.
ORGANISM(S): Pan troglodytes 
2005-08-03 | E-TABM-25 | biostudies-arrayexpress
TranscriptomicsIron regulation in P. syringae DC3000
DC3000 cultures were grown under highly controlled conditions and after the addition of iron citrate or sodium citrate to the media. In the cultures supplemented with iron, we found that cell-associated iron increased rapidly while culture densities were not significantly different over 4 hours when...
ORGANISM(S): Pseudomonas syringae pv. tomato str. DC3000 
2008-11-07 | E-GEOD-13500 | biostudies-arrayexpress
TranscriptomicsIdentifying mRNA targets of microRNA in clear cell renal cell carcinoma
A bioinformatic approach to identify targets of microRNA in cancer. Keywords: Patient sample study Samples GSM413237-GSM413270: Total RNA from 17 RCC tumors and 17 corresponding non-tumor samples was hybridized against a common reference RNA (Perou CM, Sorlie T, Eisen MB, et al. Molecular portraits...
ORGANISM(S): Homo sapiens 
2011-02-28 | E-GEOD-16441 | biostudies-arrayexpress
TranscriptomicsThe two-component system ChrSA is crucial for heme tolerance and interferes with HrrSA in heme-dependent gene regulation in Corynebacterium glutamicum
We recently showed that the two-component system (TCS) HrrSA plays a central role in the control of heme homeostasis in the Gram-positive soil bacterium Corynebacterium glutamicum. Here, we characterized the function of another TCS of this organism, ChrSA, which exhibits significant sequence similar...
ORGANISM(S): Corynebacterium glutamicum ATCC 13032 
2012-10-31 | E-GEOD-37327 | biostudies-arrayexpress
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