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ProteomicsSystematic quantitative analysis of H2A and H2B variants by targeted proteomics
Background: Histones organize DNA into chromatin through a variety of processes. Among them, a vast diversity of histone variants can be incorporated into chromatin to finely modulate its organization and functionality. Classically, the study of histone variants has largely relied on antibody-based ...
ORGANISM(S): Mus musculus (Mouse) 
2018-01-16 | PXD008358 | Pride
Srm Prm Histone variants Targeted proteomics Spermatogenesis Chromatin Proteomics 
ProteomicsStructural obstruction to full DNA replication in the chromatin of terminally differentiated skeletal muscle cells
Terminal cell differentiation is often associated with permanent withdrawal from proliferation, termed the postmitotic state. Though widespread among vertebrates and determinant for their biology, the molecular underpinnings of this state are poorly understood. Postmitotic skeletal muscle myotubes c...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2025-01-13 | MSV000096839 | MassIVE
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