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TranscriptomicsExpression data from primary human keratinocytes exposed to cytokines in vitro (IL-4, IL-13, IL-17A, IFN-alpha, IFN-gamma, TNF)
The clinical features of psoriasis, characterized by sharply demarcated scaly erythematous plaques, are typically so distinctive that a diagnosis can easily be made on these grounds alone. However, there is great variability in treatment response between individual patients, and this may reflect het...
ORGANISM(S): Homo sapiens 
2012-03-07 | E-GEOD-36287 | biostudies-arrayexpress
TranscriptomicsTranscriptome analysis of psoriasis in a large case-control sample: RNA-seq provides insights into disease mechanisms
To increase our understanding of psoriasis, we utilized RNA-seq to assay the transcriptomes of lesional psoriatic and normal skin. We sequenced polyadenylated RNA-derived cDNAs from 92 psoriatic and 82 normal punch biopsies, generating an average of ~38 million single-end 80-bp reads per sample. Com...
ORGANISM(S): Homo sapiens 
2014-01-29 | E-GEOD-54456 | biostudies-arrayexpress
UnknownStructural variation of centromeric endogenous retroviruses in human populations and their impact on cutaneous T-cell lymphoma, Sezary syndrome, and HIV infection.
Not available
S-EPMC6498702 | biostudies-literature
UnknownAssociation of β-defensin copy number and psoriasis in three cohorts of European origin.
Not available
S-EPMC3447111 | biostudies-literature
UnknownAssessment of the psoriatic transcriptome in a large sample: additional regulated genes and comparisons with in vitro models.
Not available
S-EPMC3128718 | biostudies-literature
GenomicsCollaborative Association Study of Psoriasis

The goal of this collaborative study is to combine the resources and expertise of three groups with long-standing studies of psoriasis genetics in order to identify new genetic susceptibility factors for psoriasis, a common inflammatory skin disease that affects over 4 million Americans.

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phs000019.v1.p1 | EGA
UnknownLarge-Scale Imputation of KIR Copy Number and HLA Alleles in North American and European Psoriasis Case-Control Cohorts Reveals Association of Inhibitory KIR2DL2 With Psoriasis.
Not available
S-EPMC8231283 | biostudies-literature
UnknownSafety and efficacy of tisagenlecleucel in primary CNS lymphoma: a phase 1/2 clinical trial.
Not available
S-EPMC9012129 | biostudies-literature
UnknownAnalysis of long non-coding RNAs highlights tissue-specific expression patterns and epigenetic profiles in normal and psoriatic skin.
Not available
S-EPMC4311508 | biostudies-literature
UnknownTranscriptome analysis of psoriasis in a large case-control sample: RNA-seq provides insights into disease mechanisms.
Not available
S-EPMC4057954 | biostudies-literature
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