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Since the first human conceived through in vitro fertilisation in 1978, over 8 million babies have been born by assisted reproductive technologies (ART). Although most ART babies and children seem healthy, in recent years, several human and animal model studies have evidenced a potential impact of A...
ORGANISM(S): Oryctolagus cuniculus (Rabbit) 
2021-09-08 | PXD016677 | Pride
Since the first human conceived through in vitro fertilisation in 1978, over 8 million babies have been born by assisted reproductive technologies (ART). Although most ART babies and children seem healthy, in recent years, several human and animal model studies have evidenced a potential impact of A...
ORGANISM(S): Oryctolagus cuniculus (Rabbit) 
2021-09-09 | PXD016874 | Pride
Studies on embryo cryopreservation efficiency had been focused mainly on technical and embryo factors. While structural damages can be easily evaluated, physiological damages only can be estimated by analyzing their in vitro and in vivo development to later stages. In order to determine how cryopres...
ORGANISM(S): Oryctolagus cuniculus 
The DNA, its epigenetic information and signals from the direct environment, all work together to orchestrate the development of the single fertilized oocyte into a new individual. The concept of developmental programming, attributed to the embryonic plasticity, suggests that the early life environm...
ORGANISM(S): Oryctolagus cuniculus (Rabbit) 
2022-02-15 | PXD017972 | Pride
Possible interactions between endometrium and implanting embryo in humans
ORGANISM(S): Homo sapiens 
Study question: Does storage time impact on transcriptome of slowly frozen cryopreserved human metaphase II (MII) oocytes? Summary answer: For the first time, we demonstrate that the length of cryostorage has no effect on the gene expression profile of human metaphase II oocytes. What is known alrea...
ORGANISM(S): Homo sapiens 
Investigative Study on the Impact of Cryopreservation on Mouse Embryo Development (PRJCA021988)
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