Embryonic heart

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Unknown (2822)
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human nasopharyngeal metagenome (1)

Organisms

Mus musculus (382)
Homo sapiens (98)
Danio rerio (47)
Gallus gallus (13)
Rattus norvegicus (6)
Bos taurus (5)
Arabidopsis thaliana (5)
Xenopus laevis (3)
Drosophila melanogaster (2)
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Repository

biostudies-arrayexpress (999)
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geo (534)
pride (59)
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Tissue

Brown adipose tissue (2)
Diaphragm (1)
Saliva-secreting gland (1)
Eye (1)
Embryonic tissue (1)
Skeletal muscle (1)
Olfactory bulb (1)
White adipose tissue (1)
Cardiac atrium (1)
Right proepicardium (1)
Outflow tract (1)
Rastral dorsal mesocardium (1)
Caudal dorsal mesocardium (1)
Left pacemaker cell (1)
Left side of right pacemaker cell (1)
Sinus venosus (1)
Right pacemaker cell (1)
Left proepicardium (1)
Endocardium (1)
Thymus (1)
Duodenum (1)
Colon (1)
Medulla oblongata (1)
Midbrain (1)
Stomach (1)
Pancreas (1)
Cerebral cortex (1)
Cortex of kidney (1)
Ovary (1)
Uterus (1)

Disease

Cardiovascular system disease (9)
Disease free (4)
Normal (3)
Cardiomyopathy (2)
Congenital heart disease (2)
Congential heart disease (1)
Cogenital heart disease (1)
Acute lymphocytic leukemia (1)
Cardiac defects (1)
Mild asthma (1)
Arteriosclerotic cardiovascular disease (1)
Brain cancer (1)
Dilated cardiomyopathy (1)
Down syndrome (1)
Myocardial ischemia (1)
Ovarian dysfunction (1)
Wounds and Injuries (1)

Technology Type

Mass Spectrometry (59)
Shotgun proteomics (36)
Affinity purification coupled with mass spectrometry proteomics (9)
Data-dependent acquisition (7)
Bottom-up proteomics (6)
Data-independent acquisition (6)
Mass spectrometry (5)
Mass spectrometry assay (3)
Gel-based experiment (2)
Illumina HiSeq 2000 (1)
NMR spectroscopy (1)
Top-down proteomics (1)

Instrument Platform

Illumina HiSeq 2500 (28)
Illumina NovaSeq 6000 (24)
Illumina HiSeq 4000 (18)
NextSeq 500 (17)
Illumina HiSeq 2000 (9)
Q Exactive HF-X (5)
NextSeq 2000 (3)
Single nuclei were captured using the 10x Genomics Chromium Controller. (2)
Bioanalyzer 2200 (2)
Chromium Controller (2)
GenePix 4000B [Axon Instruments] (2)
Scanning hardware (2)
NA (2)
Illumina HiSeq 1500 (2)
NextSeq 550 (2)
BD Rhapsody (1)
Cutadapt, STAR (1)
TruSeq Stranded mRNA Sample Prep Kit (Illumina) (1)
BD InFlux Cytometer (Becton-Dickinson) (1)
10x Chromium Controller (1)
Agilent G2505C (1)
Affymetrix GeneChip(R) HT Scanner (1)
GenePix 4000A [Axon Instruments] (1)
Generation III Array Scanner [Amersham] (1)
Axon- GenePix4000B (1)
418 [Affymetrix] (1)
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Illumina Genome Analyzer II (1)
Illumina NovaSeq X (1)
Illumina HiSeq 1000 (1)

Publication Date

2016 (185)
2015 (151)
2012 (120)
2010 (120)
2014 (118)
2013 (117)
2011 (113)
2025 (77)
2023 (74)
2008 (69)
2026 (61)
2021 (52)
2024 (49)
2022 (49)
2009 (48)
2020 (45)
2019 (44)
2018 (40)
2017 (40)
2007 (29)
2006 (10)
2005 (8)
2004 (4)
2003 (1)
2002 (1)

CHEBI ID

CHEBI:46229 (2)
CHEBI:17202 (2)
CHEBI:16000 (2)
CHEBI:422 (2)
CHEBI:16704 (2)
CHEBI:15891 (2)
CHEBI:18132 (2)
CHEBI:17115 (2)
CHEBI:18050 (2)
CHEBI:16865 (2)
CHEBI:44215 (2)
CHEBI:17203 (2)
CHEBI:18019 (2)
CHEBI:16015 (2)
CHEBI:17196 (2)
CHEBI:16467 (2)
CHEBI:15428 (2)
CHEBI:18012 (2)
CHEBI:17053 (2)
CHEBI:16027 (2)
CHEBI:16335 (2)
CHEBI:16919 (2)
CHEBI:16347 (2)
CHEBI:16414 (2)
CHEBI:15354 (2)
CHEBI:15603 (2)
CHEBI:16643 (2)
CHEBI:17895 (2)
CHEBI:17295 (2)
CHEBI:17596 (2)

Metabolite Name

L-Proline (3)
Guanosine (3)
Creatine (3)
Cholesterol sulfate (2)
O-phosphoethanolamine (2)
2'-Deoxyguanosine 5'-monophosphate (dGMP) (2)
L-Citrulline (2)
Nicotinamide adenine dinucleotide (NAD) (2)
N-Acetyl-D-glucosamine (2)
Taurine (2)
L-aspartic acid (2)
Betaine (2)
Thiamine (2)
Biopterin (2)
Argininosuccinic acid (2)
Glutathione disulfide (2)
L-Homoserine (2)
L-Anserine (2)
L-2-Aminoadipic acid (2)
Nicotinamide (2)
Choline (2)
Taurine (2)
Pantothenic acid (2)
L-Arginine (2)
Adenosine (2)
Cytosine (2)
Sarcosine (2)
Phosphorylcholine (2)
L-methionine (2)
L-Glutamine (2)

First Public Date

2014 (96)
2024 (78)
2026 (69)
2025 (67)
2023 (59)
2022 (50)
2019 (43)
2020 (39)
2021 (36)
2018 (33)
2017 (32)
2015 (28)
2016 (15)
2013 (12)

Modification

-17.026549 (1)
15.994915 (1)
31.989829 (1)
42.010565 (1)
57.021464 (1)
79.966331 (1)

Study type

Transcription profiling by array (598)
RNA-seq of coding RNA (148)
ChIP-seq (88)
RNA-seq of non coding RNA (26)
ChIP-chip by tiling array (23)
RNA-seq of coding RNA from single cells (19)
Methylation profiling by array (10)
Methylation profiling by high throughput sequencing (10)
Animal - High-throughput sequencing (9)
Other (9)
Unknown experiment type (7)
Single nucleus RNA sequencing (6)
Transcription profiling by RT-PCR (5)
MicroRNA profiling by array (5)
Transcription profiling by tiling array (4)
Transcription profiling by SAGE (3)
Human - High-throughput sequencing (3)
ChIP-chip by array (3)
Spatial transcriptomics by high-throughput sequencing (2)
ATAC-seq (2)
Single-nucleus ATAC-seq (1)
Baseline (1)
RIP-chip by array (1)
CLIP-Seq (1)
Plant - High-throughput sequencing (1)
Cell line - One-color microarray (1)
Plant - One-color microarray (1)
RNAi profiling by array (1)
Genotyping by array (1)
Bisulfite-seq (1)

Release Date

2015 (299)
2016 (289)
2014 (252)
2021 (240)
2022 (225)
2020 (214)
2013 (210)
2010 (208)
2011 (203)
2012 (202)
2019 (200)
2025 (196)
2018 (196)
2024 (165)
2023 (165)
2017 (165)
2008 (124)
2009 (91)
2007 (60)
2006 (27)
2026 (26)
2005 (25)
2004 (11)
2003 (9)
2002 (6)
1999 (4)
2001 (3)
2000 (3)
1997 (2)
1998 (1)

Lab affiliation

Cardiac Bioengineering group, QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia (2)
Department of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, University of Toronto (2)
Hannover Medical School, Department of Cardiology and Angiology (2)
Institut Pasteur 25 Rue du Docteur Roux Paris 75015 (2)
Leibniz Institute on Aging – Fritz Lipmann Institute (FLI), 07745 Jena, Germany (2)
University of Wisconsin-Madison (2)
Associate Professor, Center for Genomics and Systems Biology, Dept of Biology, New York University (1)
Baker Heart & Diabetes Inst. (1)
Baker Heart & Diabetes Institute (1)
Baker Heart and Diabetes Institute (1)
Biomedical Engineering Department Oregon Health & Science University Portland, OR 97239 (1)
Biophysics Department, GSI Helmholtz Center for Heavy Ion Research GmbH, Darmstadt, Germany (1)
CVRTI, University of Utah (lab head) (1)
Cardiac Bioengineering Lab, QIMR Berghofer Medical Research Institute, Brisbane, QLD, AUS (1)
Cardiac Bioengineering lab, QIMR Berghofer Medical Research Institute, Herston, QLD, AUD (1)
Cell and Developmental Biology Center, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA. (1)
Centre for Organismal Studies (COS) Heidelberg Im Neuenheimer Feld 360 69120 Heidelberg Fon +49 6221 54-6286 Fax +49 6221 54-5859 (1)
Cleveland Clinic (1)
Department of Biochemistry and Chemistry, LIMS, La Trobe University, Kingsbury Drive, Bundoora, Vic 3086, Australia (1)
Department of Biology, UNC-Chapel Hill (1)
Department of Immunology, University of Toronto, Canada Toronto General Hospital Research Institute, University Health Network, Canada (1)
Department of Immunology, University of Toronto, Canada Toronto General Hosptial Research Institute, University Health Network, Canada (1)
Department of Internal Medicine - Cardiology Division Nora Eccles Harrison Cardiovascular Research and Training Institute, Univeristy of Utah, Salt Lake City, UT, USA (1)
Department of Life Science, National Taiwan University, Taiwan (1)
Department of Medicine, Cardiology division, Lillehei Heart Institute, University of Minnesota, USA (1)
Department of Molecular Biology, Princeton University, USA (1)
Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto ON M5S 3E1, Canada (1)
Head of the Crick Mass Spectrometry Proteomics Platform (1)
Institut de Génétique et de Biologie Moléculaire et Cellulaire, 67404 Illkirch, France (1)
Institute of Cellular Biology and Pathology (1)

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Gestational palmitic acid suppresses embryonic GATA-binding protein 4 signaling and causes congenital heart disease

Dysregulated maternal fatty acid metabolism increases the risk of congenital heart disease (CHD) in offspring with an unknown mechanism, and the effect of folic acid fortification in preventing CHD is controversial. Using gas chromatography coupled to either a flame ionization detector or mass spect...

2023-03-24 | MTBLS6982 | MetaboLights

Increased Hemodynamic Load in Early Embryonic Stages Alters Endocardial to Mesenchymal Transition

Normal blood flow is essential for proper heart formation during embryonic development, as abnormal hemodynamic load (blood pressure and shear stress) results in cardiac defects seen in congenital heart disease. However, the progressive detrimental remodeling processes that relate altered blood flow...

ORGANISM(S): Gallus Gallus (ncbitaxon:9031)

2019-07-17 | MSV000084103 | MassIVE

Proteomic Profiling Assessed by Data-Independent Acquisition Mass Spectrometry Revealed Enrichment in Myofibrillogenesis in the Heart Primordium after Heartbeat Initiation in Rats.

We investigated proteomic profiling assessed by data-independent acquisition mass spectrometry (DIA-MS) in the rat heart primordia before and after heartbeat initiation at embryonic day 10.0, when heartbeat begins in rats, and in the primordial heart tube at embryonic day 11.0.

ORGANISM(S): Rattus Rattus (black Rat)

2022-06-02 | PXD032987 | JPOST Repository

Transcriptional Atlas of Cardiogenesis Maps Congenital Heart Disease Interactome

Mammalian heart development is built on highly conserved molecular mechanisms with polygenetic perturbations resulting in a spectrum of congenital heart diseases (CHD). However, the transcriptional landscape of cardiogenic ontogeny that regulates proper cardiogenesis remains largely based on candida...

ORGANISM(S): Mus musculus

2014-05-19 | E-GEOD-51483 | biostudies-arrayexpress

A 3D molecular atlas of the chick embryonic heart

We performed a detailed analysis of gene expression in the 2-day (HH12) embryonic chick heart. RNA-seq of 13 microdissected heart regions reveals regionalised expression of about 15,000 genes (Dataset 1). Of these, 131 genes that are differentially expressed (FPKM ≥20, fold change ≥1.1-4.0) within a...

ORGANISM(S): Gallus gallus

2019-10-02 | E-MTAB-7663 | biostudies-arrayexpress

Mild cold exposure mitigates ischemic heart injury through indole-3-acetamide–AHR-mediated SMAD2 proteolysis

Ambient temperature profoundly influences organismal metabolism, physiology, and disease. While cold exposure is a well-recognized risk factor for the onset of myocardial infarction (MI), its impact on the injured heart after MI remains unexplored. Here,&nb...

2026-03-03 | MTBLS13965 | MetaboLights

ChIP-seq Identification of Weakly Conserved Heart Enhancers

Accurate control of tissue-specific gene expression plays a pivotal role in heart development. However, few cardiac transcriptional enhancers have thus far been identified. Extreme non-coding sequence conservation successfully predicts enhancers active in many tissues, but fails to identify substan...

ORGANISM(S): Mus musculus

2010-08-22 | E-GEOD-22549 | biostudies-arrayexpress

Expression of microRNAs and their target mRNAs in hESC-derived cardiomyocyte clusters and in heart tissue_mRNA_data

Parallel transcription profiling of cardiomyocyte clusters derived from human embryonic stem cells. Both mRNA (this experiment) and miRNA (see E-MEXP-2655) transcription are measured and fetal and adult heart tissues are included as controls. This experiment was updated on 7th July 2011 to fix incor...

ORGANISM(S): Homo sapiens

2011-03-30 | E-MEXP-2654 | biostudies-arrayexpress

Dicer conditional knockout embryonic heart mutant vs control array

The goal is to find out the gene expression changes when Dicer was inactivated in the murine heart. Keywords: Dicer mutant Dicer gene was specifically inactivated in the mouse heart using cardiac specific Nkx2.5 Cre knock-in line. Embryonic day 11.5 heart from mutant and control hearts were compar...

ORGANISM(S): Mus musculus

2010-06-11 | E-GEOD-7343 | biostudies-arrayexpress

Late life rapamycin treatment reverses age-related heart dysfunction

We report the mRNA profile of aged mice (24 months old) fed either a control diet or a diet containing Rapamycin (14 ppm) for 3 months. After drug treatement, the hearts of the mice were removed and total mRNA was removed from the tissue. Analysis revealed that there were 700 significantly different...

ORGANISM(S): Mus musculus

2013-07-01 | E-GEOD-48043 | biostudies-arrayexpress

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