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TranscriptomicsMolecular analysis of endocrine disruption in hornyhead turbot captured from wastewater treatment plant discharge locations in Southern California
Hornyhead turbot (Pleuronichthys verticalis) captured near sewage outfalls are used as sentinel fish for monitoring exposure to industrial and agricultural chemicals of ~20 million people living in coastal southern California. Although analyses of hormones in blood and organ morphology and histology...
ORGANISM(S): Pleuronichthys verticalis 
2013-12-10 | E-MEXP-3852 | biostudies-arrayexpress
TranscriptomicsTranscriptomic effects of endocrine disruptors in zebrafish embryos
The identification of endocrine disruptive properties of chemicals certain to enter the aquatic environment relies on toxicity tests with fish, assessing adverse effects on reproduction and sexual development. The demand for quick, reliable endocrine disruption (ED) assays favored the use of fish em...
ORGANISM(S): Danio rerio 
2014-03-06 | E-GEOD-44263 | biostudies-arrayexpress
ProteomicsQuantitative proteomic profiling of estrogenic sexual endocrine perturbation in zebrafish embryos
Endocrine disruption (ED) can trigger far-reaching effects on environmental populations, justifying a refusal of market approval for chemicals with ED properties. For the assessment of ED effects on development and reproduction, regulatory decisions mostly rely on apical endpoints from in vivo testi...
ORGANISM(S): Danio rerio (Zebrafish) (Brachydanio rerio) 
2023-02-25 | PXD036868 | Pride
Zebrafish embryos Endocrine disruptors Lc-ms/ms 
ProteomicsQuantitative proteomic profiling of androgenic sexual endocrine perturbation in zebrafish embryos
Endocrine disruption (ED) can trigger far-reaching effects on environmental populations, justifying a refusal of market approval for chemicals with ED properties. For the assessment of ED effects on development and reproduction, regulatory decisions mostly rely on apical endpoints from in vivo testi...
ORGANISM(S): Danio rerio (Zebrafish) (Brachydanio rerio) 
2023-02-25 | PXD036875 | Pride
Zebrafish embryos Endocrine disruptors Lc-ms/ms 
ProteomicsQuantitative proteomic profiling of anti-estrogenic sexual endocrine perturbation in zebrafish embryos
Endocrine disruption (ED) can trigger far-reaching effects on environmental populations, justifying a refusal of market approval for chemicals with ED properties. For the assessment of ED effects on development and reproduction, regulatory decisions mostly rely on apical endpoints from in vivo testi...
ORGANISM(S): Danio rerio (Zebrafish) (Brachydanio rerio) 
2023-02-25 | PXD036869 | Pride
Zebrafish embryos Endocrine disruptors Lc-ms/ms 
ProteomicsQuantitative proteomic profiling of anti-androgenic sexual endocrine perturbation in zebrafish embryos
Endocrine disruption (ED) can trigger far-reaching effects on environmental populations, justifying a refusal of market approval for chemicals with ED properties. For the assessment of ED effects on development and reproduction, regulatory decisions mostly rely on apical endpoints from in vivo testi...
ORGANISM(S): Danio rerio (Zebrafish) (Brachydanio rerio) 
2023-02-25 | PXD036867 | Pride
Zebrafish embryos Endocrine disruptors Lc-ms/ms 
UnknownDesigning Endocrine Disruption Out of the Next Generation of Chemicals.
Not available
S-EPMC4125359 | biostudies-literature
UnknownToxic Alerts of Endocrine Disruption Revealed by Explainable Artificial Intelligence.
Not available
S-EPMC11934200 | biostudies-literature
GenomicsSRC-1 targets ADAM22: an ER-independent mechanism of tumour progression in endocrine resistance
We profile the binding of Steroid Receptor Co-activator (SRC1) in LY2 cells, a tamoxifen-resistant cell line, in the presence and absence of tamoxifen using ChIP-sequencing technology. The development of breast cancer resistance to endocrine therapy results from an increase in cellular plasticity le...
ORGANISM(S): Homo sapiens 
2011-11-01 | E-GEOD-28987 | biostudies-arrayexpress
UnknownHow to Differentiate General Toxicity-Related Endocrine Effects from Endocrine Disruption: Systematic Review of Carbon Disulfide Data.
Not available
S-EPMC8952789 | biostudies-literature
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