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Background: Development and application of transcriptomics-based gene classifiers for ecotoxicological applications lag far behind those of human biomedical science. Many such classifiers discovered thus far lack vigorous statistical and experimental validations, with their stability and reliabilit...
ORGANISM(S): Danio rerio 
LC-MS/MS data obtained from livers of 17 adult mangrove rivulus exposed to different doses of 17-alpha-ethinylestradiol during early development. All fish acclimations, treatments, experimental design, and data anlyses were performed in Frederic Silvestre's laboratory at the University of Namur, Bel...
ORGANISM(S): Kryptolebias Marmoratus (ncbitaxon:37003) 
2018-08-13 | MSV000082815 | MassIVE
PI: Experiments and fish exposures were performed in the laboratory of Frederic Silvestre at the University of Namur (Belgium). Proteomics contact: Proteomics sample preparation and biological mass spectrometry were performed in the laboratory of Prof. Dietmar Kueltz at UC Davis (CA). LC-MS/MS data ...
ORGANISM(S): Kryptolebias Marmoratus (ncbitaxon:37003) 
2018-08-13 | MSV000082814 | MassIVE
LC-MS/MS data obtained from gonads of 17 adult mangrove rivulus exposed to different doses of 17-alpha-ethinylestradiol during early development. All fish acclimations, treatments, experimental design, and data anlyses were performed in Frederic Silvestre's laboratory at the University of Namur, Bel...
ORGANISM(S): Kryptolebias Marmoratus (ncbitaxon:37003) 
2018-08-13 | MSV000082816 | MassIVE
Developmental Exposure to Endocrine-Disrupting Chemicals Alters Gene Expression in Myometrium of Exposed Animals
Fetal human fetal testes (8-11 weeks post-fertilization [WPF]) were cut into small pieces (~1 mm3 ) and 4-6 pieces/testis (depending of the age or size of the gonad) were insert into the muscle of the left back of two twin female mice. One week after surgery, one mouse was exposed by drinking water ...
ORGANISM(S): Homo sapiens 
In this study, we aimed to engineer an in vitro model that better resembles the glandular architecture and hemodynamic perfusion of the native thyroid than current in vitro models, and that can better evaluate the effect of potential endocrine disrupting chemicals (EDCs) on the thyroid. We construct...
ORGANISM(S): Homo sapiens 
Fetal human fetal testes (8-11 weeks post-fertilization [WPF]) were cut into small pieces (~1 mm3 ) and 4-6 pieces/testis (depending of the age or size of the gonad) were insert into the muscle of the left back of two twin female mice. One week after surgery, one mouse was exposed by drinking water ...
ORGANISM(S): Homo sapiens 
Evaluating the toxicity of two endocrine disrupting chemicals, Raloxifene and Resorcinol using a larval zebrafish transcriptomic approach
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