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Barley cysteine endoprotease B (HvEPB) is an important enzyme in plant biology and food production. Pilot-scale fed-batch fermentation with Komagataella phaffii in minimal FM22 medium enabled controlled recombinant HvEPB (r-HvEPB) secretion. Peptidomics across four technological brewing matrices - r...
ORGANISM(S): Komagataella phaffii Hordeum vulgare subsp. vulgare 
2026-07-28 | PXD067323 | Pride
MSP-MS of Cathepsin B and Cathepsin K pH 4.6 pH 7.2
ORGANISM(S): Synthetic Construct (ncbitaxon:32630) 
2022-02-28 | MSV000088932 | MassIVE
Using a methylated-DNA enrichment technique (MIRA) in combination with whole genome tiling arrays, we have characterized by MIRA-chip the entire B cell ‘methylome’ of an individual human at 100 base pair resolution. Methylated fragments in genomic DNA extracted from B cells were enriched with the M...
ORGANISM(S): Homo sapiens 
Diffuse Large B-Cell Lymphoma (DLBCL) is a biologically heterogeneous and clinically aggressive disease. Here, we explore the role of BET bromodomain proteins in DLBCL, using integrative chemical genetics and functional epigenomics. We observe highly asymmetric loading of BRD4 at enhancers, with app...
ORGANISM(S): Homo sapiens 
Many mammalian genes are occupied by paused RNA polymerase II (pol II) at promoter-proximal regions on both sides of transcription start sites (TSSs). However, the consequences of pol II pausing on gene expression and cell biology are not fully understood. Here we report that genetic ablation of t...
ORGANISM(S): Mus musculus 
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