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We used 2', 3'-cyclic phosphate cDNA synthesis and Illumina sequencing to identify and quantify metal-ion-independent endoribonuclease cleavage sites in host and viral RNAs. To make cDNA libraries, we exploited the 2’, 3’-cyclic phosphate at the end of RNA fragments produced by RNase L and other met...
ORGANISM(S): Homo sapiens 
The poly A binding protein RB47 was purified from C. reinhardtii chloroplasts and was found to have endoribonuclease activity. MS analysis suggested that an internal non-conserved linker (NCL)sequence was absent from the native protein. Recombinant, full length RB47 protein, including the NCL did no...
ORGANISM(S): Chlamydomonas reinhardtii 
2018-10-27 | PXD004285 | Pride
A long form (tRNase ZL) of tRNA 3' processing endoribonuclease (tRNase Z, or 3' tRNase) can cleave any target RNA at any desired site under the direction of artificial small guide RNA (sgRNA). We discovered in human kidney 293 cell extracts various new small noncoding RNAs (ncRNAs) including 5'-half...
ORGANISM(S): Homo sapiens 
We used 2', 3'-cyclic phosphate cDNA synthesis and Illumina sequencing to identify and endoribonuclease cleavage sites in host and viral RNAs during HCV infection of Huh7.5.1 cells
ORGANISM(S): Homo sapiens 
2022-08-06 | GSE72144 | GEO
The endoribonuclease YbeY is linked to proper cellular morphology and virulence in Brucella abortus
We used 2', 3'-cyclic phosphate cDNA synthesis and Illumina sequencing to identify and quantify metal-ion-independent endoribonuclease cleavage sites in host and viral RNAs.
ORGANISM(S): Poliovirus 1 hepatitis C virus genotype 1a Homo sapiens 
2014-02-07 | GSE52489 | GEO
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