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ProteomicsMassive intein content in Anaeramoeba reveals new aspects of intein mobility in eukaryotes
Inteins are self-splicing protein elements found in viruses and all three domains of life. How the DNA encoding these selfish elements spreads within and between genomes is poorly understood, particularly in eukaryotes where inteins are scarce. Here we show that the nuclear genomes of three strains ...
ORGANISM(S): Anaeramoeba flamelloides 
2023-11-30 | PXD045607 | Pride
Lc-ms/ms Intein Protist Anaeramoeba 
GenomicsOff-target analysis of intein, AAVLINK, and StitchR delivery ABE8e systems in HEK293T cells
Off-target analysis of intein, AAVLINK, and StitchR delivery ABE8e systems in HEK293T cells
PRJNA1533476 | ENA
ProteomicsSplit intein mdx skeletal muscle proteomics
Duchenne muscular dystrophy is a rare and lethal neuromuscular disease caused by loss-of-function mutations in the dystrophin protein that provides structural integrity to striated muscle fibers. Mice with loss-of-function mutations for the Dmd gene encoding dystrophin (mdx-4cv) were treated with mi...
ORGANISM(S): Mus musculus (Mouse) 
2025-11-06 | PXD062324 | Pride
Aav therapy Split-intein Duchenne muscular dystrophy Skeletal muscle Lcms 
ProteomicsNon-intein splicing of RB47 - Activation of an Endoribonuclease by Non-intein Protein Splicing
The poly A binding protein RB47 was purified from C. reinhardtii chloroplasts and was found to have endoribonuclease activity. MS analysis suggested that an internal non-conserved linker (NCL)sequence was absent from the native protein. Recombinant, full length RB47 protein, including the NCL did no...
ORGANISM(S): Chlamydomonas reinhardtii 
2018-10-27 | PXD004285 | Pride
Rb47 C. reinhardti Chloroplast Intein 
GenomicsComparative evaluation of intein, AAVLINK, and StichR ABE8e systems targeting DMD-E50 in HEK293T cells
Comparative evaluation of intein, AAVLINK, and StichR ABE8e systems targeting DMD-E50 in HEK293T cells
PRJNA1533477 | ENA
UnknownAP-APSE dpol intein: A novel family A DNA polymerase intein domain.
Not available
S-EPMC3092948 | biostudies-literature
UnknownA DnaB intein in Rhodothermus marinus: indication of recent intein homing across remotely related organisms.
Not available
S-EPMC21518 | biostudies-literature
GenomicsComparison of editing efficiencies of intein, AAVLINK, and StitchR delivery ABE8e systems at the mouse TA
Comparison of editing efficiencies of intein, AAVLINK, and StitchR delivery ABE8e systems at the mouse TA
PRJNA1533474 | ENA
UnknownMassive intein content in Anaeramoeba reveals aspects of intein mobility in eukaryotes.
Not available
S-EPMC10710043 | biostudies-literature
OtherOff-target analysis of intein, AAVLINK, and StitchR delivery ABE8e systems in HEK293T cells
In this study, off-target analysis of intein, AAVLINK, and StitchR based ABE8e systems by flow sorting and deep sequencing.
ORGANISM(S): Homo sapiens 
2026-09-30 | GSE348336 | GEO
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