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Background: Exposure to dichlorvos (DDVP), an organophosphorus pesticide, is known to result in neurotoxicity as well as other metabolic perturbations. However, the molecular causes of DDVP toxicity are poorly understood, especially in cells other than neurons and muscle cells. To obtain a better un...
ORGANISM(S): Danio rerio 
This model describes the central carbon and energy metabolism of E. coli growing under anaerobic conditions. For complete information about the model see: 'Deciphering the physiological response of Escherichia coli under high ATP demand Simon Boecker, Giulia Slaviero, Thorben Schramm, Witold Szyman...
2022-02-13 | MODEL2202020001 | BioModels
Medium-chain acyl-coenzyme A (CoA) dehydrogenase (MCAD) catalyzes crucial steps in mitochondrial fatty acid oxidation, a process that is of key relevance for maintenance of energy homeostasis, especially during high metabolic demand. To gain insight into the metabolic consequences of MCAD defici...
ORGANISM(S): Mus musculus 
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