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MetabolomicsMultiomics analysis of residual feed intake regulation in calves by intestinal microbiota-mediated epigenetic modifications
Feed efficiency is a critical trait affecting the economic profitability and environmental sustainability of livestock production. Residual Feed Intake (RFI), as a key metric for feed efficiency, effectively reflects differences in energy utilization for maintenance and production. This study aims t...
2026-04-20 | MTBLS14315 | MetaboLights
MetabolomicsPlasma 1H-NMR metabolic and amino acid profiles of newborn piglets from two lines divergently selected for residual feed intake

Together with environmental factors, physiological maturity at birth is a major determinant for neonatal survival and postnatal development in mammalian species. Maturity at birth is the outcome of complex mechanisms of intra-uterine development and maturation during the end of gestation. In pig ...

2023-02-16 | MTBLS2137 | MetaboLights
MetabolomicsHabitual Coffee Intake Shapes the Gut Microbiome and Modifies Host Physiology and Cognition

Coffee influences multiple physiological processes, including gut function, stress, cognition, and the microbiome. However, the mechanisms underlying these effects remain poorly understood. In this study, we examined coffee’s impact on the microbiota–gut–brain axis—a bidirectional communication p...

2026-04-07 | MTBLS13494 | MetaboLights
MetabolomicsHabitual Coffee Intake Shapes the Gut Microbiome and Modifies Host Physiology and Cognition: double-blind, randomised, parallel design

Coffee influences multiple physiological processes, including gut function, stress, cognition, and the microbiome. However, the mechanisms underlying these effects remain poorly understood. In this study, we examined coffee’s impact on the microbiota–gut–brain axis—a bidirectional communication p...

2026-03-26 | MTBLS13401 | MetaboLights
TranscriptomicsPeripheral blood mononuclear cells gene expression reflects adaptive response and metabolic damage associated to the intake of diets with an unbalanced proportion of macronutrients
Gene expression studies in peripheral blood mononuclear cells (PBMC) can provide knowledge that would be difficult to obtain using other types of biological samples, as these cells can reflect overall response of the body to a specific stimulus, such as diet. Here, we aimed to study the impact of su...
ORGANISM(S): Rattus norvegicus 
2015-12-07 | E-GEOD-54897 | biostudies-arrayexpress
TranscriptomicsEffects of Sex, Strain, and Energy Intake on Hallmarks of Aging in Mice
Calorie restriction (CR) is the most robust non-genetic intervention to universally delay the onset of age-related diseases and extend mean and maximum lifespan. However, species, strain, sex, diet, age of onset, and level of CR are emerging as important variables to consider for a successful CR res...
ORGANISM(S): Mus musculus 
2016-06-27 | E-GEOD-81959 | biostudies-arrayexpress
GenomicsCagriSema drives weight loss in rats by reducing energy intake and preserving energy expenditure
CagriSema drives weight loss in rats by reducing energy intake and preserving energy expenditure
PRJNA1253981 | ENA
ProteomicsProtein-restricted diet increases circulating FGF21 levels and necessitating an increase in energy intake to maintain body weight in healthy human individuals
Dietary protein restriction has been shown to increase energy expenditure and to improve insulin sensitivity in mice, but it is unknown whether humans exhibit similar phenotype to a prolonged eucaloric protein-restricted diet that meet daily protein minimum requirements. We hypothesize that a protei...
ORGANISM(S): Mus musculus (Mouse) Homo sapiens (Human) 
2025-04-22 | PXD047177 | Pride
Human Energy intake Body weight Healthy Fgf21 
TranscriptomicsHypothalamic gene expression of appetite regulators in a cancer-cachectic mouse model [Dataset 1]
Appetite is frequently affected in cancer patients, leading to anorexia and consequently insufficient food intake. In this study, we report on hypothalamic gene expression profile of a cancer cachectic mouse model with increased food intake. In this model, mice bearing C26 colon adenocarcinoma have ...
ORGANISM(S): Mus musculus 
2013-11-14 | E-GEOD-44080 | biostudies-arrayexpress
TranscriptomicsSubcutaneous adipose tissue (SAT) gene expression patterns between weight control and regaining weight subjects
Objective: This work aimed at identifying and characterizing differences in subcutaneous adipose tissue (SAT) gene expression patterns between subjects succeeding weight control against subjects regaining weight 6 months after a low calorie diet program. Methods: Weight-reduced obese subjects from 8...
ORGANISM(S): Homo sapiens 
2010-09-30 | E-GEOD-19494 | biostudies-arrayexpress
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