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ProteomicsFast & High Throughput LC-MS Characterization, and Peptide Mapping of Engineered AAV Capsids Using LC-MS/MS
Adeno-associated virus (AAV) has emerged as a leading platform for gene therapy. With a skyrocketing rate of AAV research and the prevalence of many new engineered capsids being investigated in preclinical and clinical trials, capsid characterization plays an important role in serotype confirmation ...
ORGANISM(S): Adeno-associated virus 9 
2023-03-11 | PXD035837 | Pride
Peptide map. Aav capsids Engineered aav capsids Lcms Msms 
UnknownRationally engineered novel AAV capsids for intra-articular gene delivery.
Not available
S-EPMC10907215 | biostudies-literature
UnknownAAV Gene Therapy Drug Development and Translation of Engineered Ocular and Neurotropic Capsids: A Systematic Review Using Natural Language Processing.
Not available
S-EPMC12662786 | biostudies-literature
ProteomicsAnalysis of Protein Carrier AAV by LC-MS/MS
AAV is widely used for efficient delivery of DNA payloads. The extent to which the AAV capsid can be used to deliver a protein payload is unexplored. Here, we report engineered AAV capsids that directly package proteins – Protein Carrier AAV (pcAAV). Nanobodies inserted into the interior of the caps...
ORGANISM(S): Adeno-associated virus 2 Srivastava/1982 
2025-05-07 | PXD054767 | Pride
Lc-msms Adeno-associated virus Dia Maxquant 
UnknownSystemic administration of novel engineered AAV capsids facilitates enhanced transgene expression in the macaque CNS.
Not available
S-EPMC9840684 | biostudies-literature
UnknownFast and high-throughput LC-MS characterization, and peptide mapping of engineered AAV capsids using LC-MS/MS.
Not available
S-EPMC9563341 | biostudies-literature
UnknownComparative Study of Liver Gene Transfer With AAV Vectors Based on Natural and Engineered AAV Capsids.
Not available
S-EPMC4700115 | biostudies-literature
UnknownRationally Engineered AAV Capsids Improve Transduction and Volumetric Spread in the CNS.
Not available
S-EPMC5503098 | biostudies-literature
GenomicsAdeno-associated virus 9
Systemic administration of novel engineered AAV capsids facilitates enhanced transgene expression in the macaque CNS
PRJNA895493 | ENA
UnknownRapid evolution of blood-brain-barrier-penetrating AAV capsids by RNA-driven biopanning.
Not available
S-EPMC7841218 | biostudies-literature
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