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ProteomicsStructure-Activity Relationships of ENMs
Current nano-SARs are often based on univariate assessments and fail to provide tiered views on ENM-induced bio-effects. Here we pioneered a multi-hierarchical nano-SAR assessment for a representative ENM, Fe2O3, by metabolomics and proteomics analyses. The established nano-SAR profile allows visual...
ORGANISM(S): Homo sapiens (Human) 
2019-11-12 | PXD010614 | Pride
Proteomics Metabolomics Sar Enms 
UnknownTracking translocation of industrially relevant engineered nanomaterials (ENMs) across alveolar epithelial monolayers in vitro.
Not available
S-EPMC4387897 | biostudies-literature
UnknownNeeds and challenges for assessing the environmental impacts of engineered nanomaterials (ENMs).
Not available
S-EPMC5433198 | biostudies-literature
UnknownLong-term effects of mobile exoneuromusculoskeleton (ENMS)-assisted self-help telerehabilitation after stroke.
Not available
S-EPMC10965606 | biostudies-literature
ProteomicsProteome changes in monocytic THP-1 cells induced by 31 engineered nanomaterials
Here, we investigated a panel of 31 engineered nanomaterials (ENMs) with different core chemistries and surface modifications using conventional cytotoxicity assays coupled with omics-based approaches. Proteomics analysis were conducted in order to monitor changes in cells proteome exposed to ENMs. ...
ORGANISM(S): Homo sapiens (Human) 
2021-09-09 | PXD019267 | Pride
Immunotoxicology Proteomics Mass spectrometry Nanomaterials Nanotoxicology 
Genomics
Comparing BMMSCs treated with PBS (Con group) or EM-eNMs (EM-eNMs group)
PRJNA1270042 | ENA
MetabolomicsMulti-hierarchical profiling the structure-activity relationships of engineered nanomaterials at nano-bio interfaces
Increasing concerns over the possible risks of nanotechnology necessitates breakthroughs in structure-activity relationship (SAR) analyses of engineered nanomaterials (ENMs) at nano-bio interfaces. However, current nano-SARs are often based on univariate assessments and fail to provide tiered views ...
2020-01-23 | MTBLS721 | MetaboLights
TranscriptomicsToxicity mechanisms of ZnO UV-filters used in sunscreens toward the model cyanobacteria Synechococcus elongatus PCC7942
Zinc oxide (ZnO) nanoparticles are commonly used in sunscreens for their UV-filtering properties. Their growing use can lead to their release into ecosystems, raising question about their toxicity. Effects of these engineered nanomaterials (ENMs) on cyanobacteria, which are important primary produce...
ORGANISM(S): Synechococcus elongatus PCC 7942 = FACHB-805 
2019-06-05 | GSE102914 | GEO
TranscriptomicsMulti-parametric profiling of a large panel of engineered nanomaterials (ENM) points to surface chemistry as a key determinant of nanomaterial effects
Monocytic, cancer derived THP-1 cells were exposed to 31 different engineered nanomaterials (ENMs) with different core chemistries and surface modifications for 24 hours.
ORGANISM(S): Homo sapiens 
2020-12-01 | GSE148705 | GEO
TranscriptomicsCarbon nanotubes, but not graphene oxide, trigger chemokine production in primary human macrophages via MyD88 dependent NF-kB Pathway
The growing medical application of engineered nanomaterials (ENMs) necessitates better understanding of their molecular toxicity mechanisms governing immune effects. In the present study, a comprehensive mechanistic in vitro assessment of two carbon-based ENMs, single-walled carbon nanotubes (SWCNTs...
ORGANISM(S): Homo sapiens 
2017-09-30 | GSE83516 | GEO
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