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UnknownA course with a difference. Fighting infectious diseases with technology and knowledge-transfer.
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S-EPMC1796770 | biostudies-literature
ProteomicsShigella hijacks the exocyst to cluster macropinosomes for efficient vacuolar escape
Shigella flexneri invades host cells by entering within a bacteria-containing vacuole (BCV). In order to establish its niche in the host cytosol, the bacterium ruptures its BCV. Contacts between S. flexneri BCV and infection-associated macropinosomes (IAMs) formed in situ have been reported to enhan...
ORGANISM(S): Shigella flexneri 5a str. M90T 
2021-08-11 | PXD020161 | Pride
Macropinosomes Shigella 
ProteomicsSalmonella mediated intracellular niche control by SCV size regulation
Salmonella is a human and animal pathogen causing gastro-enteric diseases worldwide. The key feature of Salmonella infection is its entry into intestinal epithelial cells within a Salmonella-Containing Vacuole (SCV). This original compartment is distinct from empty macropinosomes formed around the...
ORGANISM(S): Salmonella enterica subsp. enterica serovar Typhimurium 
2020-01-09 | PXD012825 | Pride
Membrane trafficking Membrane rupture Magnetic extraction Tubule formation Macropinosome Membrane fusion Salmonella containing vacuole Snare Salmonella enterica serovar typhimurium Svat 
TranscriptomicsTranscription profiling of A549 cells after Pneumococcus 6B ST90 and TIGR4 infection
Compared A549 epithelial cells 2 hrs post-challenge with 6B ST90 CC156 lineage F and TIGR4.
ORGANISM(S): Homo sapiens 
2020-11-10 | E-MTAB-9603 | biostudies-arrayexpress
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