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TranscriptomicsTranscription profiling by array of human HT29 colon cancer cells to investigate the role of Caveolin 1, E-Cadherin, Enolase 2 and PKCa on resistance to methotrexate
A summary of the work associated to these microarrays is the following:; Methotrexate (MTX) is one of the earliest cytotoxic drugs used in cancer therapy, and despite the isolation of multiple other folate antagonists, methotrexate maintains its significant role as a treatment for different types of...
ORGANISM(S): Homo sapiens 
2008-10-25 | E-GEOD-11440 | biostudies-arrayexpress
Genomics
RIP-seq from ENO1 (Enolase 1)
PRJNA1213289 | ENA
GenomicsExon Skipping of Ste20-Like Kinase Enhances Glycolysis and Tumor Progression by Activating Enolase 1 mediated Phosphoenolpyruvate Production
Exon Skipping of Ste20-Like Kinase Enhances Glycolysis and Tumor Progression by Activating Enolase 1 mediated Phosphoenolpyruvate Production
PRJNA1273951 | ENA
UnknownAn arrestin-1 surface opposite of its interface with photoactivated rhodopsin engages with enolase-1.
Not available
S-EPMC7212649 | biostudies-literature
UnknownCirculating enolase 1 as a diagnostic biomarker for early-stage breast cancer.
Not available
S-EPMC12534435 | biostudies-literature
ProteomicsPlasma Extracellular Vesicle-Associated enolase 1 as a Diagnostic Biomarker for Early-Stage 1 Breast Cancer
For successful treatment of breast cancer, early and efficient diagnosis is paramount. However, the diagnosis of breast cancer in the earliest stage, stage 1, is challenging as small tumors are often left undetected by conventional imaging techniques. Additionally, 8 out of 10 breast masses are clas...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2025-01-31 | MSV000097016 | MassIVE
UnknownIdentification of Enolase 1 and Thrombospondin-1 as serum biomarkers in HBV hepatic fibrosis by proteomics.
Not available
S-EPMC3734151 | biostudies-literature
UnknownImpaired enolase 1 glycolytic activity restrains effector functions of tumor-infiltrating CD8+ T cells.
Not available
S-EPMC6824424 | biostudies-literature
TranscriptomicsExon Skipping of Ste20-Like Kinase Enhances Glycolysis and Tumor Progression by Activating Enolase 1 mediated Phosphoenolpyruvate Production
Dysregulated RNA splicing is activated in tumors; however, the metabolic landscape and consequent implications of this process remain largely unexplored. In this study, we identified exon skipping in Ste20-like kinase (SLK), resulting in a variant isoform of SLK (SLKv), which promotes glycolysis in ...
ORGANISM(S): Homo sapiens 
2025-06-17 | GSE299345 | GEO
ProteomicsCholine kinase promotes glycolysis and tumor growth by phosphorylating and activating enolase 1
Tumor cells exhibit aberrantly upregulated glycolysis, in which glycolytic enzyme enolase 1 (ENO1) plays a critical role. However, how ENO1 activity is dynamically regulated in tumor cells remains elusive. Here, we demonstrate that hypoxic stimulation promotes the binding of p38 MAP kinase to cholin...
ORGANISM(S): Acyrthosiphon pisum (Pea aphid) 
2026-09-05 | PXD058061 | Pride
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