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In animals and plants extracellular ATP (eATP) functions as signal and regulates the immune response. During inflammation intestinal bacteria are exposed to elevated eATP originating from the mucosa. However, whether bacteria respond to eATP is unclear. Here we show that non-pathogenic Escherichi...

2025-08-28 | MTBLS12905 | MetaboLights

The bacterial lipid membrane, consisting both of fatty acid (acyl) tails and polar head groups, responds to changing conditions through alteration of either the acyl tails and/or head groups. This plasticity is critical for cell survival as it allows maintenance of both the protective nature of t...

2021-05-17 | MTBLS2080 | MetaboLights
We used the previously designed oligonucleotide-based microarray (Burgmann et al. Environmental Microbiology 2007, 9: 2742-2755) to detect the transcripts of R. pomeroyi DSS-3 genes when the cells were cultured under steady-state carbon (glucose), nitrogen (ammonium), phosphorus (phosphate), or sulf...
ORGANISM(S): Ruegeria pomeroyi DSS-3 
Ultimately, the genotype of a cell and its interaction with the environment determine the cell’s biochemical state. While the cell’s response to a single stimulus has been studied extensively, a conceptual framework to model the effect of multiple environmental stimuli applied concurrently is not a...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2015-07-20 | PXD002371 | Pride
Metaproteomics is an essential approach to analyse the in situ metabolic activity of microbes across various environments. In such highly diverse environmental samples, the functionality of specific microorganisms of importance often remains underexplored due to the protein inference problem arising...
ORGANISM(S): Polaribacter sp. Aurantivirga 
2025-09-29 | PXD057908 | Pride
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