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TranscriptomicsEP400 Deposits H3.3 into Promoters and Enhancers During Gene Activation
Purpose: We wanted to know how histone variants H3.3 and H2AZ are deposited into genes and enhancers during gene activation Methods: U2OS cells were harvested at 70% confluency with formaldehyde crosslinking for ChIP-seq without crosslinking for RNA-seq. ChIP DNA were purified through standard chrom...
ORGANISM(S): Homo sapiens 
2015-12-18 | E-GEOD-73742 | biostudies-arrayexpress
UnknownMerkel cell polyomavirus recruits MYCL to the EP400 complex to promote oncogenesis.
Not available
S-EPMC5640240 | biostudies-literature
GenomicsThe role of the Ep400/Kat5 chromatin remodeling complex in the cranial neural crest and orofacial clefting
The role of the Ep400/Kat5 chromatin remodeling complex in the cranial neural crest and orofacial clefting
PRJNA888785 | ENA
ProteomicsUnique structural features of the human NuA4/TIP60 acetyltransferase and chromatin remodeling complex
The human NuA4/TIP60 co-activator complex, a fusion of the yeast SWR1 and NuA4 complexes, both incorporates the histone variant H2A.Z into nucleosomes and acetylates histones H4/H2A/H2A.Z to play crucial roles regulating gene expression and maintaining genome stability. Our cryo-EM studies show that...
ORGANISM(S): Homo sapiens (Human) 
2024-08-08 | PXD053207 | Pride
Nua4/tip60 acetyltransferase Ep400 complex Chromatin remodeling complex Ncp 
UnknownProtein arginine methyltransferase 5 sustains Tip60-EP400 complex via SRSF1 in Merkel cell carcinoma.
Not available
S-EPMC12373721 | biostudies-literature
TranscriptomicsThe role of the Ep400/Kat5 chromatin remodeling complex in the cranial neural crest and orofacial clefting
The cranial neural crest plays a fundamental role in orofacial development and morphogenesis. As a pluripotent and dynamic cell population, the cranial neural crest is undergoing vast transcriptional alterations throughout embryogenesis and the formation of facial structures. These transcriptional c...
ORGANISM(S): Mus musculus 
2023-03-23 | GSE215109 | GEO
UnknownThe Tip60/Ep400 chromatin remodeling complex impacts basic cellular functions in cranial neural crest-derived tissue during early orofacial development.
Not available
S-EPMC10079831 | biostudies-literature
UnknownChromatin Modifier EP400 Regulates Oocyte Quality and Zygotic Genome Activation in Mice.
Not available
S-EPMC11132066 | biostudies-literature
GenomicsMCPyV ST activates Max target genes by recruiting TRRAP/EP400 complex
MCPyV ST activates Max target genes by recruiting TRRAP/EP400 complex
PRJNA287013 | ENA
UnknownEp400 deficiency in Schwann cells causes persistent expression of early developmental regulators and peripheral neuropathy.
Not available
S-EPMC6541636 | biostudies-literature
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