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TranscriptomicsIsolation and next generation sequencing of epididymal extracellular vesicles reveals segmental patterns of miRNA expression and a potential mechanism for modification of the sperm epigenome.
Interest in the sperm epigenome continues to grow in view of the realization that it is vulnerable to dynamic modifications arising from a variety of paternal environment exposures and that this legacy can serve as an important determinant of intergenerational inheritance. It has been postulated tha...
ORGANISM(S): Mus musculus 
2016-08-25 | E-GEOD-79500 | biostudies-arrayexpress
TranscriptomicsEpididymosomes convey different repertoires of miRNAs throughout the epididymis
Epididymosomes are small membrane vesicles (50-500nm) secreted by epididymal epithelial cells and involved in post-testicular sperm maturation. While their role in protein transfer to the sperm membrane is well acknowledged, we unveil here their capacity to vehicle microRNAs (miRNAs), which are pote...
ORGANISM(S): Bos taurus 
2013-07-01 | E-GEOD-44365 | biostudies-arrayexpress
GenomicsEpididymosomes convey different repertoires of miRNAs throughout the epididymis
Epididymosomes are small membrane vesicles (50-500nm) secreted by epididymal epithelial cells and involved in post-testicular sperm maturation. While their role in protein transfer to the sperm membrane is well acknowledged, we unveil here their capacity to vehicle microRNAs (miRNAs), which are pote...
ORGANISM(S): synthetic construct Bos taurus 
2013-07-01 | GSE44365 | GEO
UnknownIsolation of CD63-positive epididymosomes from human semen and its application in improving sperm function.
Not available
S-EPMC11483612 | biostudies-literature
UnknownProteomic Profiling of Mouse Epididymosomes Reveals their Contributions to Post-testicular Sperm Maturation.
Not available
S-EPMC6427233 | biostudies-literature
GenomicsPhthalate exposure to adult mice alters non-coding RNAs in cauda epididymosomes
Phthalate exposure to adult mice alters non-coding RNAs in cauda epididymosomes
PRJNA1110781 | ENA
UnknownCharacterisation of mouse epididymosomes reveals a complex profile of microRNAs and a potential mechanism for modification of the sperm epigenome.
Not available
S-EPMC4994100 | biostudies-literature
GenomicsBos taurus
Epididymosomes convey different repertoires of miRNAs throughout the epididymis
PRJNA189565 | ENA
GenomicsPhthalate exposure to adult mice alters non-coding RNAs in cauda epididymosomes
Extracellular vesicles (EVs) are known to contain important cargo of biologically active and regulatory molecules including small non-coding RNA (sncRNA). EVs from cauda epididymis play crucial role in post-testicular maturation of sperm. We assessed levels of cauda epididymosomes sncRNAs following ...
ORGANISM(S): Mus musculus 
2025-10-13 | GSE267272 | GEO
UnknownHeavy Chronic Intermittent Ethanol Exposure Alters Small Noncoding RNAs in Mouse Sperm and Epididymosomes.
Not available
S-EPMC5809758 | biostudies-literature
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