Epigenetic drugs

Show results for

Unknown (1707)
Genomics (552)
Transcriptomics (463)
Proteomics (49)
Methylation profiling (42)
Other (14)
Metabolomics (8)
Genomic (6)
Models (2)

Organisms

Homo sapiens (497)
Mus musculus (163)
Allexis (33)
Arabidopsis thaliana (33)
Entamoeba histolytica HM-1:IMSS-A (33)
Escherichia coli (33)
Homo sapiens (33)
Listeria monocytogenes (33)
Rattus norvegicus (22)
Plasmodium falciparum (5)
Drosophila melanogaster (5)
Saccharomyces cerevisiae (4)
Schizosaccharomyces pombe (2)
mixed sample (2)
Danio rerio (2)
Arabidopsis thaliana (2)
Toxoplasma gondii (2)
Oxytricha trifallax (1)
Salmonella enterica subsp. enterica (1)
Strongyloides ratti (1)
Hordeum vulgare subsp. spontaneum (1)
Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 (1)
Xenopus laevis (1)
Gadus morhua (1)
Acinetobacter baumannii (1)
Candida albicans (1)
Nakaseomyces glabratus (1)
synthetic construct (1)
cellular organisms (1)
Human alphaherpesvirus 1 (1)

Organisms

Homo sapiens (237)
Mus musculus (77)
Rattus norvegicus (8)
Plasmodium falciparum (3)
Babesia sp. MO1 (1)
Nakaseomyces glabratus (1)
Entamoeba histolytica (1)
Drosophila melanogaster (1)
Toxoplasma gondii (1)

Repository

ENA (364)
biostudies-arrayexpress (344)
geo (306)
EGA (58)
pride (33)
MassIVE (11)
MetaboLights (8)
dbGaP (6)
BioModels (2)
jPOST (2)
LINCS (2)
PanoramaPublic (2)
iProX (1)

Tissue

Cell culture (12)
Epithelial cell (4)
Brain (3)
T cell (3)
Bone marrow (2)
Colon (2)
Fibroblast (2)
Permanent cell line cell (2)
Primary cell (2)
B cell (1)
Breast cancer cell line (1)
C2C12 cell (1)
Cell suspension culture (1)
Colon epithelial cell (1)
Diploid cell (1)
Early embryonic cell (1)
Embryo (1)
Embryonic stem cell (1)
Epithelial cell of cervix (1)
HeLa cell (1)
Hepatocyte (1)
Lymphoblast (1)
Melanocyte (1)
Monocyte (1)
Neuron (1)
Neuronal cell line (1)
Nucleus accumbens (1)
Oral squamous cell carcinoma cell (1)
Skeletal muscle myoblast (1)

Disease

Breast cancer (5)
Colon cancer (3)
Glioblastoma (2)
Primary tumor (1)
Melanoma (1)
Bladder transitional carcinoma (1)
Gastric cancer (1)
Colorectal adenocarcinoma (1)
Acute T cell leukemia (1)
Bone osteosarcoma (1)
Brain cancer (1)
Brain glioblastoma multiforme (1)
Cachexia (1)
Cardiovascular system disease (1)
Cervix carcinoma (1)
Chagas disease (1)
Chronic myelogenous leukemia (1)
Disease free (1)
Inflammation (1)
Malignant neoplasm of ovary (1)
Myeloid leukemia (1)
Neurological alteration (1)

Technology Type

Mass Spectrometry (33)
Shotgun proteomics (21)
Mass spectrometry (7)
Bottom-up proteomics (6)
Affinity purification coupled with mass spectrometry proteomics (4)
Data-dependent acquisition (4)
Illumina HiSeq 2000 (2)
GCP (2)
Mass spectrometry (2)
Gel-based experiment (2)
Illumina HumanWG-6 (1)
Illumina HumanMethylation450K, Illumina HiSeq 2500, Illumina InfiniumCoreExome-24v1-1_A, ILLUMINA (1)
ILLUMINA, Illumina HiSeq 2500, Illumina HumanMethylation450K, Illumina InfiniumCoreExome-24v1-1_A (1)
Illumina HiSeq 2500, ILLUMINA (1)
ILLUMINA, Illumina HiSeq 2500 (1)
Illumina_450K, Illumina_HumanHT-12_V4, ILLUMINA, Illumina HiSeq 2000 (1)
Illumina HiSeq 2000, Infinium HumanMethylation450 BeadChip (1)
Illumina_450K (1)
GeneChip HTA 2.0 (1)
Mass spectrometry assay (1)
Data-independent acquisition (1)
MSE (1)
SRM/MRM (1)
SWATH MS (1)

Instrument Platform

Illumina NovaSeq 6000 (17)
Illumina HiSeq 2000 (13)
NextSeq 500 (8)
NextSeq 550 (4)
Liquid Chromatography MS - positive - reverse phase (4)
Illumina HiSeq 2500 (3)
Illumina HiSeq 4000 (3)
Orbitrap Fusion Lumos (3)
Q Exactive (3)
Complete Genomics (2)
GenePix 4000B [Axon Instruments] (2)
DNBSEQ-G400 (2)
Liquid Chromatography MS - negative - reverse phase (2)
Illumina Genome Analyzer Iix (1)
MoFlo Legacy cell sorter (Beckman Coulter) (1)
PC (1)
IScan (1)
Illumina Genome Analyzer IIx (1)
DNA Microarray Scanner BA [Agilent Technologies] (1)
Illumina NovaSeq X (1)
GridION (1)
NextSeq 2000 (1)
MinION (1)
LTQ Orbitrap Elite (1)
LTQ Orbitrap Velos (1)
Orbitrap Exploris 240 (1)
Orbitrap Exploris 480 (1)
Q Exactive HF (1)
Q Exactive Plus (1)
ZenoTOF 7600 (1)

Publication Date

2025 (72)
2013 (66)
2024 (64)
2015 (62)
2022 (47)
2014 (46)
2021 (38)
2026 (37)
2011 (37)
2012 (36)
2016 (34)
2010 (33)
2023 (27)
2019 (22)
2020 (19)
2018 (18)
2017 (18)
2008 (13)
2009 (10)
2007 (4)
2006 (2)
2005 (2)

CHEBI ID

CHEBI:17562 (3)
CHEBI:19062 (3)
CHEBI:20607 (3)
CHEBI:16020 (3)
CHEBI:16335 (3)
CHEBI:17802 (3)
CHEBI:178092 (2)
CHEBI:178091 (2)
CHEBI:19068 (2)
CHEBI:178090 (2)
CHEBI:19688 (2)
CHEBI:21891 (2)
CHEBI:19229 (2)
CHEBI:19065 (2)
CHEBI:19227 (2)
CHEBI:89487 (2)
CHEBI:20129 (2)
CHEBI:45996 (2)
CHEBI:69426 (2)
CHEBI:20794 (2)
CHEBI:17509 (2)
CHEBI:16750 (2)
CHEBI:68467 (2)
CHEBI:19228 (2)
CHEBI:16708 (2)
CHEBI:16704 (2)
CHEBI:19702 (2)
CHEBI:17596 (2)
CHEBI:136341 (1)
CHEBI:136224 (1)

Metabolite Name

Pseudouridine (3)
Cytidine (3)
Adenosine (3)
3'-O-Methylbatatasin III (2)
2-methylguanosine (2)
1-methylinosine (2)
2-methyladenosine (2)
8-methyladenosine (2)
6-methyladenosine (2)
3-methylpseudouridine (2)
1-methylpseudouridine (2)
4-methylcytidine (2)
1,2-Epoxyhexadecane (2)
5-Phenylvaleric acid (2)
Hymexazol O-glucoside (2)
3-methyluridine (2)
2-Nitrophenol (2)
2'-O-methylinosine (2)
3-Methylphenylacetic acid (2)
2'-O-methyluridine (2)
Colchicine (2)
2'-O-methylguanosine (2)
N-Acetylhistamine (2)
2'-O-methylcytidine (2)
8-Hydroxyguanosine (2)
Aucubin (2)
2'-O-methyladenosine (2)
1,11-Undecanedicarboxylic acid (2)
3-methylcytidine (2)
Uracil (2)

IsPrivate

False (2)

Submitter Keywords

Not Peer Reviewed (1)

First Public Date

2025 (53)
2024 (51)
2014 (39)
2022 (33)
2026 (32)
2021 (29)
2023 (26)
2019 (22)
2017 (21)
2020 (20)
2015 (15)
2018 (11)
2016 (9)
2013 (3)

Classification

protozoa (6)
fungi (1)

Modelling Approach

Differential equation model (1)

Study type

Transcription profiling by array (132)
RNA-seq of coding RNA (51)
Methylation profiling by array (48)
ChIP-seq (35)
Methylation profiling by high throughput sequencing (21)
ChIP-chip by tiling array (12)
Cell line - High-throughput sequencing (7)
ATAC-seq (4)
MicroRNA profiling by array (4)
ChIP-chip by array (3)
Comparative genomic hybridization by array (3)
Other (3)
Cell line - Methylation microarray (2)
Bisulfite-seq (2)
DNA-seq (2)
RNA-seq of total RNA (2)
RNA-seq of non coding RNA from single cells (1)
Human - Methylation microarray (1)
Human - High-throughput sequencing (1)
Animal - High-throughput sequencing (1)
Transcription profiling by tiling array (1)
MicroRNA profiling by high throughput sequencing (1)
Hi-C (1)
RIP-seq (1)
ScATAC-seq (1)
Genotyping by high throughput sequencing (1)
RNA-seq of coding RNA from single cells (1)

Release Date

2022 (248)
2021 (214)
2023 (189)
2020 (165)
2024 (140)
2025 (122)
2019 (122)
2018 (120)
2015 (114)
2016 (112)
2017 (105)
2013 (95)
2014 (85)
2012 (58)
2011 (49)
2010 (43)
2026 (26)
2008 (16)
2009 (15)
2006 (6)
2007 (3)
2005 (1)
2004 (1)
2001 (1)

Lab affiliation

1. Barts Cancer Institute, Queen Mary University of London; Charterhouse Square, London EC1M 6BQ, UK. 2. Instituto de Parasitología y Biomedicina “López-Neyra” (IPBLN-CSIC); E-18016 Granada, Spain. (1)
Biomolecular Mass Spectrometry and Proteomics Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences Utrecht University (1)
CRUK Beatson Institute, Switchback Road, Glasgow G61 1BD, UK. (1)
Cellzome, a GSK company, Heidelberg, Germany (1)
Chair of Proteomics and Bioanalytics, Technical University of Munich (TUM), 85354 Freising, Germany (1)
Chemistry Institute, LADETEC, Proteomics Laboratory, UFRJ, RJ, Brazil. (1)
Core Facility Proteomics Hannover Medical School Carl-Neuberg-Str. 1 30625 Hannover Germany (1)
Department of Biochemistry, Albert Einstein College of Medicine, Bronx, NY 10461, United States (1)
Department of Biochemistry, Biophysics and General Pathology, University of Campania “Luigi Vanvitelli”, Vico L. De Crecchio 7, 80138 Napoli, IT (1)
Department of Cell and Molecular Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA-92037 (1)
Department of Chemistry and Chemical Biology, Woo Lab, Harvard University, US (1)
Department of Genetics, Washington University School of Medicine, St. Louis, MO, USA; The Edison Family Center for Genome Sciences and Systems Biology, Washington University School of Medicine, St. Louis, MO, USA; McDonnell Genome Institute, Washington University School of Medicine, St. Louis, MO, USA (1)
Department of Innovative Technologies in Medicine & Dentistry, University of "G. d'Annunzio" of Chieti-Pescara, Chieti, Italy (1)
Department of Microbiology, Blavatnik Institute, Harvard Medical School, Boston, MA, 02115, USA Division of Molecular Medicine, Boston Children's Hospital, Boston, MA, 02115, USA (1)
Department of Molecular Mechanisms of Disease University of Zurich Winterthurerstr. 190 8057 Zurich, Switzerland (1)
European Institute of Oncology (1)
Genome Sciences, University of Washington, Seattle, WA (1)
Head of Proteomics (1)
Institu Pasteur (1)
Institute for Molecular Medicine I Medical Faculty Heinrich-Heine-University Duesseldorf Universitaetsstrasse 1 40225 Duesseldorf Germany (1)
Institute of Biochemistry and Technical Biochemistry Department Biochemistry of Cellular Biomedical Systems University of Stuttgart (1)
Institute of Molecular Systems Biology, ETH Zurich, Zurich, Switzerland (1)
Instituto Carlos Chagas, FIOCRUZ Parana (1)
Mass Spectrometry/Proteomics Facility, Netherlands Cancer Institute, Amsterdam, Netherlands. (1)
Medical University of South Carolina, Department of Neuroscience, Charleston, SC, USA (1)
Molecular Proteomics Laboratory, Biological Medical Research Center, Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany (1)
Penn Epigenetics Institute Department of Biochemistry and Biophysics Smilow Center for Translational Research University of Pennsylvania School of Medicine (1)
ProGenTomics Laboratory of Pharmaceutical Biotechnology, Ghent University, Belgium (1)
Proteomics Core Facility, Biomedical Research Institute, Seoul National University Hospital (1)
Proteomics center, Erasmus MC (1)

Previous page
1 / 285
You're on page 1
page 2
page 3
page 4
page 5
page ...
page 285
Next page

Sort by:

Relevance

Page size

Robust ligand-protein interaction inference reveals off-targets of epigenetic drugs

Detecting target engagement is a major challenge in drug discovery. To this end, thermal proteome profiling (TPP) offers unbiased assessment of system-wide ligand-protein interactions. However, its most sensitive assay format lacks statistical methods with false discovery rate-control. Here, we pres...

ORGANISM(S): Homo sapiens (Human)

2020-10-29 | PXD016640 | Pride

Tpp Epigenetic drugs

Epigenetic reader ZMYND11 noncanonical function restricts HNRNPA1-mediated stress granule formation and oncogenic activity

Epigenetic reader ZMYND11 noncanonical function restricts HNRNPA1-mediated stress granule formation and oncogenic activity, PPI of ZMYND11 in LNCap

ORGANISM(S): Homo Sapiens

2024-08-28 | PXD055421 |

TNBC organoid sc-multiome seq data treated with epigenetic drugs

PRJNA1219492 | ENA

Role of different epigenetic drugs in reshaping murine melanoma tumor microenvironment

PRJNA1068500 | ENA

Role of different epigenetic drugs in reshaping murine melanoma tumor microenvironment [Array]

PRJNA1068512 | ENA

Epigenetic editing and epi-drugs: a combination strategy to simultaneously target KDM4 as a novel anticancer approach.

Not available

S-EPMC12177974 | biostudies-literature

Trials with 'epigenetic' drugs: an update.

Not available

S-EPMC5528349 | biostudies-literature

DNA methylation analysis of neuroblastoma cell lines treated with epigenetic drugs

The impact of drugs inhibiting DNA methylation (5-aza-2'-deoxycytodine, DAC) and EZH2 (EPZ-6438) on the neuroblastoma methylome was analyzed in two neuroblastoma cell lines. Parallel analyses investigated associated changes in histone modification and RNA expression. The neuroblastoma cell lines Be(...

ORGANISM(S): Homo sapiens

2016-09-08 | E-GEOD-80243 | biostudies-arrayexpress

Repositioning FDA-Approved Drugs in Combination with Epigenetic Drugs to Reprogram Colon Cancer Epigenome.

Not available

S-EPMC5292054 | biostudies-literature

Drugs and Epigenetic Molecular Functions. A Pharmacological Data Scientometric Analysis.

Not available

S-EPMC8311652 | biostudies-literature

Previous page
1 / 285
You're on page 1
page 2
page 3
page 4
page 5
page ...
page 285
Next page

Sort by:

Relevance

Page size

2845 Results

Show results for

Organisms

Organisms

Repository

Tissue

Disease

Technology Type

Instrument Platform

Publication Date

CHEBI ID

Metabolite Name

IsPrivate

Submitter Keywords

First Public Date

Classification

Modelling Approach

Study type

Release Date

Lab affiliation

Tags

OmicsDI is part of the ELIXIR infrastructure

Tweets