Epitope-tagged nav1.7 mouse

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Mass Spectrometry (2)
Affinity purification coupled with mass spectrometry proteomics (1)
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2018 (2)

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Mass Spectrometry Laboratory, Target Discovery Institute, University of Oxford, The Old Road Campus, Oxford, OX3 7FZ, UK (1)
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Mapping protein interactions of sodium channel NaV1.7 using epitope-tagged gene targeted mice

The voltage-gated sodium channel NaV1.7 plays a critical role in pain pathways. As well as action potential propagation, NaV1.7 regulates neurotransmitter release, integrates depolarizing inputs over long periods and regulates transcription. In order to better understand these functions, we generate...

ORGANISM(S): Mus musculus (Mouse)

2018-01-15 | PXD005155 | Pride

Mice brain tissue IP experiment

This is a experment want to fish out the proteins in the mice brain can interact with sodium chanel protein Nav1.7, immuno precipatation and lab free mass spectrmetry were used to identify Nav1.7 Interation parter proteins.

ORGANISM(S): Mus musculus (Mouse)

2018-01-15 | PXD004926 | Pride

Mice brain

Mapping protein interactions of sodium channel Na<sub>V</sub>1.7 using epitope-tagged gene-targeted mice.

Not available

S-EPMC5793798 | biostudies-literature

Sensory neuron-derived Na<sub>V</sub>1.7 contributes to dorsal horn neuron excitability.