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ProteomicsFormation of ER-lumenal intermediates during export of Plasmodium proteins containing transmembrane-like hydrophobic sequences
REX3RQLSE:Pf332:C-S11:DSLE is exported and is diffusely localised in the red blood cell cytoplasm (Fig 3A). Mutation of the PEXEL sequence (REX3AQLSE:Pf332:C-S11:DSLE), results in the protein being retained in the parasite (Fig 3C), and addition of a C-terminal SDEL sequence (REX3RQLSE:Pf332:C-S11:S...
ORGANISM(S): Plasmodium falciparum 
2023-03-28 | PXD036904 | Pride
Plasmodium Proteomics Lc-ms/ms 
UnknownYos9p and Hrd1p mediate ER retention of misfolded proteins for ER-associated degradation.
Not available
S-EPMC3315801 | biostudies-literature
UnknownER retention is imposed by COPII protein sorting and attenuated by 4-phenylbutyrate.
Not available
S-EPMC5464768 | biostudies-literature
UnknownCalnexin mediates the maturation of GPI-anchors through ER retention.
Not available
S-EPMC7705322 | biostudies-literature
UnknownThe ER retention protein RER1 promotes alpha-synuclein degradation via the proteasome.
Not available
S-EPMC5587320 | biostudies-literature
ProteomicsRegulation of proteome by the proteasome upon ER stress
HeLa cells were with Tunicamycin or Thapsigargin for 8 hours in the presence or absence of MG132 or untreated. Cells were lysed by addition of HEPES 50 mM pH7.9 with 5% SDS. Proteins were precipitated with methanol/chloroforme and the proteins were resolubilized in 8 M Urea and digested with trypsin...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2019-04-30 | MSV000083736 | MassIVE
TranscriptomicsRNA-seq in MCF-7 cells which had been exposed to arsenic
In this study, we examined the effect of inorganic arsenic (iAs) on the estrogen response (E2) in MCF-7 cells that are estrogen receptor positive/progesterone receptor positive (ER+/PR+). Understanding the changes in the transcriptomic response after iAs exposure and the retention of such responses...
ORGANISM(S): Homo sapiens 
2020-10-21 | E-MTAB-9498 | biostudies-arrayexpress
MetabolomicsInulin gel-mediated delivery of Clostridium butyricum spores protects against acute kidney injury via regulation of ER-mitochondria contacts
Acute kidney injury (AKI) progression is closely associated with gut microbiota dysbiosis. However, the detailed mechanism remains unclear. In this study, we found that patients with AKI had decreased beneficial bacteria and reduced butyric acid levels in the intestine. Furthermore, butyrate allevia...
2026-09-17 | MTBLS15607 | MetaboLights
UnknownER retention receptor, MoERR1 is required for fungal development and pathogenicity in the rice blast fungus, Magnaporthe oryzae.
Not available
S-EPMC5430845 | biostudies-literature
ProteomicsDynamic Organellar Mapping in yeast exposed to ER stress
Sophisticated techniques are available for systematic studies of yeast cell biology. However, it remains challenging to investigate protein subcellular localization changes on a proteome-wide scale. Here, we apply Dynamic Organellar Maps (DOMs) by label-free mass spectrometry to detect localization ...
ORGANISM(S): Saccharomyces cerevisiae Saccharomyces cerevisiae (Baker's yeast) 
2025-12-03 | PXD061764 | Pride
Tunicamycin Dynamic organellar maps Yeast Er stress Dtt Subcellular localization 
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