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TranscriptomicsChromatin immunopreciptiation of H2AZ in mouse embryonic stem cells and neural precursor cells
Elucidating how chromatin organization influences gene expression patterns and ultimately cell fate is fundamental to understanding development and disease. Histone variants have emerged as key regulators of genome function by creating specialized chromatin domains. The histone variant H2AZ plays an...
ORGANISM(S): Mus musculus 
2009-01-22 | E-TABM-556 | biostudies-arrayexpress
TranscriptomicsEffects of TiO2 and Ag nanoparticles on polyhydroxybutyrate biosynthesis by activated sludge bacteria
Manufactured nanomaterials (MNMs) are increasingly incorporated into consumer products that are disposed into sewage. In wastewater treatment, MNMs adsorb to activated sludge biomass where they may impact biological wastewater treatment performance, including nutrient removal. Here, we studied MNM e...
ORGANISM(S): mixed sample 
2014-12-03 | E-GEOD-63781 | biostudies-arrayexpress
TranscriptomicsTranscriptional Reversion of Cardiac Myocyte Fate During Mammalian Cardiac Regeneration.
Rationale: Neonatal mice have the capacity to regenerate their hearts in response to injury, but this potential is lost after the first week of life. The transcriptional changes that underpin mammalian cardiac regeneration have not been fully characterized at the molecular level. Objective: The obje...
ORGANISM(S): Mus musculus 
2014-12-20 | E-GEOD-64403 | biostudies-arrayexpress
TranscriptomicsGenome-wide analysis of EGFR inhibitor erlotinib treatment in Head and neck, squamous cell carcinoma's FADU, SQ20B and Cal 27
Chronic inflammation plays a significant role in tumor promotion, migration and invasion. Using microarray analysis, we observed a profound increase in genes involved in pro-inflammatory pathways in epidermal growth factor receptor inhibitor (EGFRI)-treated head and neck squamous cell carcinoma (HNS...
ORGANISM(S): Homo sapiens 
2014-04-08 | E-GEOD-45891 | biostudies-arrayexpress
TranscriptomicsPatterns of histone H3 Lysine 27 monomethylation and erythroid cell-type specific gene expression [expression]
ERYTHROID CELL-TYPE SPECIFIC GENE EXPRESSION Post-translational histone modifications, acting alone or in a context-dependent manner, influence numerous cellular processes via their regulation of gene expression. Monomethylation of histone H3 lysine 27 (K27me1) is a poorly understood histone modific...
ORGANISM(S): Homo sapiens 
2011-12-06 | E-GEOD-32135 | biostudies-arrayexpress
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