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ProteomicsThe Fgf/Erf/NCoR1/2 repressive axis controls trophoblast cell fate
Here, we demonstrate that upon inhibition of the Fgf/Erk pathway in mouse trophoblast stem cells (TSCs), the Ets2 repressor factor (Erf) interacts with components of the Nuclear Receptor Corepressor Complex 1 and 2 (NCoR1 and NCoR2). Upon attenuation of Fgf signalling, unphosphorylated, nuclear Erf ...
ORGANISM(S): Mus musculus (Mouse) 
2023-04-26 | PXD037892 | Pride
Trophoblast stem cells Erf Ncor2 Ncor1 
GenomicsErf chromatin binding-sites in E13.5 mouse embryo fibroblasts
We show that reduced dosage of ERF, which encodes an inhibitory ETS transcription factor directly bound by ERK1/2 , causes complex craniosynostosis (premature fusion of the cranial sutures) in humans and mice. Features of this newly recognized clinical disorder include multiple suture synostosis, cr...
ORGANISM(S): Mus musculus 
2013-01-15 | E-GEOD-42936 | biostudies-arrayexpress
TranscriptomicsThe Submergence Tolerance Regulator Sub1A Mediates Stress-responsive Expression of AP2/ERF Transcription Factors
Rice NSF45K microarray experiment to dissect submergence tolerance response in submergence tolerant rice plant, M202(Sub1): We previously characterized the rice (Oryza sativa L.) Sub1 locus encoding three Ethylene Responsive Factor (ERF) transcriptional regulators. Genotypes carrying the Sub1A-1 a...
ORGANISM(S): Oryza sativa 
2010-03-08 | E-GEOD-17704 | biostudies-arrayexpress
TranscriptomicsA gene regulatory network involving the class II ERF transcriptional repressors in leaf senescence of Arabidopsis thaliana
Leaf senescence is the final developmental process that includes the mobilization of nutrients from old leaves to newly growing tissues. The progression of leaf senescence requires dynamic but coordinated changes of gene expression. Although several transcription factors (TFs) are known to be involv...
ORGANISM(S): Arabidopsis thaliana 
2013-07-02 | E-GEOD-41053 | biostudies-arrayexpress
GenomicsThe Fgf/Erf/NCoR1/2 repressive axis controls trophoblast cell fate
The Fgf/Erf/NCoR1/2 repressive axis controls trophoblast cell fate
PRJNA818025 | ENA
GenomicsGenome-wide association analysis on five isolated populations - Erasmus Rucphen Family (ERF) Study
ERF is embedded in the Genetic Research in Isolated Population (GRIP) program. Genealogy of GRIP is available from its founding (1600-1650). For ERF, we selected 22 related (first and second degree, non-consanguineous) couples living in GRIP between 1850-1900, and having at least six children baptiz...
EGAS00001001134 | EGA
GenomicsEpigenetic inactivation of ERF reactivates γ-globin expression in β-thalassemia [ChIP-seq]
Epigenetic inactivation of ERF reactivates γ-globin expression in β-thalassemia [ChIP-seq]
PRJNA673718 | ENA
GenomicsEpigenetic inactivation of ERF reactivates γ-globin expression in β-thalassemia [RNA-seq]
Epigenetic inactivation of ERF reactivates γ-globin expression in β-thalassemia [RNA-seq]
PRJNA673717 | ENA
TranscriptomicsThe Fgf/Erf/NCoR1/2 repressive axis controls trophoblast cell fate
Placental development relies on coordinated cell fate decisions governed by signalling inputs. However, little is known about how signalling cues are transformed into repressive lineage-specific transcriptional signatures. Here, we demonstrate that upon inhibition of the Fgf/Erk pathway in mouse tro...
ORGANISM(S): Mus musculus 
2023-04-26 | GSE199024 | GEO
GenomicsErf chromatin binding-sites in E13.5 mouse embryo fibroblasts
We show that reduced dosage of ERF, which encodes an inhibitory ETS transcription factor directly bound by ERK1/2 , causes complex craniosynostosis (premature fusion of the cranial sutures) in humans and mice. Features of this newly recognized clinical disorder include multiple suture synostosis, cr...
ORGANISM(S): Mus musculus 
2013-01-15 | GSE42936 | GEO
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