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ProteomicsERK activation waves coordinate mechanical cell competition leading to collective onslaught of bacterially-infected cells
In this study, we investigated how biochemical signaling, and in particular extracellular signal-regulated kinase (ERK) activity waves, coordinate the mechanical battle between Listeria monocytogenes infected and surrounder uninfected epithelial cells. We explored the collective infected cell extrus...
ORGANISM(S): Listeria monocytogenes Canis familiaris (Dog) (Canis lupus familiaris) 
2024-12-18 | PXD055809 | Pride
Host-pathogen interactions Cell competition Collective cell extrusion Listeria monocytogenes Shigella flexneri Zebrafish models Bacterial infection Erk activation waves Cell biomechanics Epithelial cells 
UnknownRedundant roles of EGFR ligands in the ERK activation waves during collective cell migration.
Not available
S-EPMC8548211 | biostudies-literature
UnknownRetrograde ERK activation waves drive base-to-apex multicellular flow in murine cochlear duct morphogenesis.
Not available
S-EPMC7935486 | biostudies-literature
UnknownControl of osteoblast regeneration by a train of Erk activity waves.
Not available
S-EPMC7864885 | biostudies-literature
UnknownOscillatory ERK Signaling and Morphology Determine Heterogeneity of Breast Cancer Cell Chemotaxis via MEK-ERK and p38-MAPK Signaling Pathways.
Not available
S-EPMC9952091 | biostudies-literature
UnknownOptogenetically engineered Ca2+ oscillation-mediated DRP1 activation promotes mitochondrial fission and cell death.
Not available
S-EPMC10323238 | biostudies-literature
UnknownLow-affinity ligands of the epidermal growth factor receptor are long-range signal transmitters in collective cell migration of epithelial cells.
Not available
S-EPMC11717429 | biostudies-literature
TranscriptomicsGene expression analysis to identify target genes activated after preBCR signaling
The sequential activation of distinct developmental gene networks governs the ultimate identity of a cell, but the mechanisms by which downstream programs are activated are incompletely understood. The preB-cell receptor (preBCR) is an important checkpoint of B-cell development and essential for a p...
ORGANISM(S): Mus musculus 
2015-12-14 | E-GEOD-73562 | biostudies-arrayexpress
TranscriptomicsGene expression analysis to identify Klf2 target genes in B-cell progenitors [+Klf2]
The sequential activation of distinct developmental gene networks governs the ultimate identity of a cell, but the mechanisms by which downstream programs are activated are incompletely understood. The preB-cell receptor (preBCR) is an important checkpoint of B-cell development and essential for a p...
ORGANISM(S): Mus musculus 
2015-12-14 | E-GEOD-73559 | biostudies-arrayexpress
TranscriptomicsGene expression analysis to identify Klf2 target genes in B-cell progenitors [Klf2_KO]
The sequential activation of distinct developmental gene networks governs the ultimate identity of a cell, but the mechanisms by which downstream programs are activated are incompletely understood. The preB-cell receptor (preBCR) is an important checkpoint of B-cell development and essential for a p...
ORGANISM(S): Mus musculus 
2015-12-14 | E-GEOD-73560 | biostudies-arrayexpress
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