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Plant alkaloids represent a diverse group of nitrogen-containing natural products. These compounds are considered valuable in drug discovery and development. High-throughput identification of such plant secondary metabolites in complex plant extracts is essential for drug discovery, lead optimizatio...
2023-12-12 | MTBLS2914 | MetaboLights
An untargeted metabolomics approach using UPLC-ESI-QTOF-MS was performed to explore the metabolome of iceberg lettuce and the changes related to storage time and genetics. Two cultivars with different browning susceptibility, fast- browning (FB) and slow-browning (SB) were studied juts after cutting...
2017-08-03 | MTBLS343 | MetaboLights
Untargeted metabolomics has the potential to improve the predictivity of in vitro toxicity models and therefore may aid the reduction of expensive and laborious animal models. Here we describe a chronic nephrotoxicity study conducted on a human renal proximal tubular epithelial cell line (RPTEC/TERT...
2015-09-07 | MTBLS140 | MetaboLights
Transcriptional profiles of [ESI+]
Transcription Profiles of [ESI+] and Set3C loss of function
We profile the transcriptional landscapes associated with acquisition of [ESI+], a prion scaffolded by Snt1, a core component of the Set3C histone deacetylase. We find that acquisition of [ESI+] leads to expression of otherwise silent, heterochromatic loci, proposing a new molecular means by which s...
ORGANISM(S): Saccharomyces cerevisiae 
2020-02-29 | GSE117624 | GEO
We used porous graphitized carbon-LC-ESI-MS/MS to separate and detect released N- and O-glycan isomers from mammalian model glycoproteins using negative mode resonance activation CID-MS/MS. By interrogating similar fragment spectra from closely related glycan isomers that differ only in arm position...
ORGANISM(S): Bos Taurus (ncbitaxon:9913) Homo Sapiens (ncbitaxon:9606) 
2019-04-15 | MSV000083688 | MassIVE
We report the transcriptional profiles of the [ESI+] prion, as well as snt1∆, set3∆, and hos2∆ diploid cells.
ORGANISM(S): Saccharomyces cerevisiae 
2020-02-29 | GSE128672 | GEO
Eriocheir sinensis isolate:Esi-2015 Genome sequencing and assembly
Comparative analysis of salt-responsive phosphoproteins in maize leaves using Ti4+-IMAC enrichment and ESI-Q-TOF MS
ORGANISM(S): Zea mays (Maize) 
2012-12-14 | PXD000027 | Pride
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