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ModelsSen2021 - HTimmR - A generic human CD4+ T-cell model
A generic genome-scale metabolic model (GEMs) of human CD4+ T-cells. Several cell-specific GEMs for CD4+ T-cell subsets such as Th1, Th2, Th17 and iTreg cells derived from "HTimmR" are included as additional files. The model formats are compatible with RAVEN v.2.0 toolbox.
2023-03-29 | MODEL2101270002 | BioModels
UnknownPathogenic implications for autoimmune mechanisms derived by comparative eQTL analysis of CD4+ versus CD8+ T cells.
Not available
S-EPMC5352142 | biostudies-literature
UnknownAllele-specific expression changes dynamically during T cell activation in HLA and other autoimmune loci.
Not available
S-EPMC7135372 | biostudies-literature
MetabolomicsCirculating Metabolites in Progression to Islet Autoimmunity and Type 1 Diabetes

AIMS/HYPOTHESIS: Metabolic dysregulation may precede the onset of type 1 diabetes. However, these metabolic disturbances and their specific role in disease initiation remain poorly understood. In this study, we examined whether children who progress to type 1 diabetes have a cir...

2022-01-19 | MTBLS802 | MetaboLights
ProteomicsIdentification of global inhibitors of cellular glycosylation
Small molecule inhibitors of glycosylation enzymes can be valuable tools for dissecting glycan functions and present great potential as drug discovery candidates. Most screening campaigns for inhibitors of glycosyltransferases have been limited to in vitro enzyme assays using recombinant enzymes, wh...
ORGANISM(S): Homo sapiens (Human) 
2023-03-11 | PXD029623 | Pride
Cell-based glycan array O-glycosylation Sars-cov-2 Compound library screen Glycosylation inhibitor 53 golgi fragmentation Glycosyltransferases 
UnknownGWAS for male-pattern baldness identifies 71 susceptibility loci explaining 38% of the risk.
Not available
S-EPMC5691155 | biostudies-literature
MetabolomicsDynamics of Plasma Lipidome in Progression to Islet Autoimmunity and Type 1 Diabetes: Type 1 Diabetes Prediction and Prevention Study (DIPP)
Type 1 diabetes (T1D) is one of the most prevalent autoimmune diseases among children in Western countries. Earlier metabolomics studies suggest that T1D is preceded by dysregulation of lipid metabolism. Here we used a lipidomics approach to analyze molecular lipids in a prospective series of 428 pl...
2018-07-16 | MTBLS620 | MetaboLights
UnknownGenetic risk factors for pneumonia differ by patient subgroup.
Not available
S-EPMC12860974 | biostudies-literature
UnknownAltered Gene Expression Associated with microRNA Binding Site Polymorphisms.
Not available
S-EPMC4619707 | biostudies-literature
UnknownRegScan: a GWAS tool for quick estimation of allele effects on continuous traits and their combinations.
Not available
S-EPMC4293375 | biostudies-literature
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