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ProteomicsDefining targets of the bacterial ADP-ribosyltransferase EspJ
Tyrosine phosphorylation is key for signal transduction from exogeneous stimuli, including the defence against pathogenic microbes. Pathogens have acquired mechanisms to subvert protein phosphorylation as a means to control host immune responses and facilitate invasion and dissemination. The bacteri...
ORGANISM(S): Homo sapiens (Human) 
2018-03-16 | PXD008533 | Pride
Ehec Human Adp-ribosyltransferase Lc-ms/ms 
UnknownBroad-Spectrum Regulation of Nonreceptor Tyrosine Kinases by the Bacterial ADP-Ribosyltransferase EspJ.
Not available
S-EPMC5893879 | biostudies-literature
UnknownThe Escherichia coli effector EspJ blocks Src kinase activity via amidation and ADP ribosylation.
Not available
S-EPMC4284639 | biostudies-literature
ProteomicsThe E. coli effector EspJ blocks Src kinase activity via amidation and ADP-ribosylation
In vitro ADP-ribosylated Src-K295M was separated by SDS-PAGE and the Coomassie stained protein band excised and digested with either trypsin, thermolysin or elastase. All digests were analysed by nanoLC-MS/MS using Higher-energy C-trap Dissociation (HCD) as well as Electron-Transfer Dissociation (ET...
ORGANISM(S): Homo sapiens (Human) 
2014-12-19 | PXD001461 | Pride
Amidation Src kinase Adp-ribosylation Espj 
TranscriptomicsGene expression induced in Escherichia coli O157:H7 upon exposure to model apple juice
Escherichia coli O157:H7 has caused serious outbreaks of foodborne illness via transmission in a variety of food vehicles, including unpasteurized apple juice, dried salami, and spinach. To understand how this pathogen responds to the multiple stresses of the food environment, we compared global tr...
ORGANISM(S): Escherichia coli 
2010-05-25 | E-GEOD-11052 | biostudies-arrayexpress
UnknownThe EHEC-host interactome reveals novel targets for the translocated intimin receptor.
Not available
S-EPMC4269881 | biostudies-literature
UnknownThe Type III Secretion System Effector SeoC of Salmonella enterica subsp. salamae and S. enterica subsp. arizonae ADP-Ribosylates Src and Inhibits Opsonophagocytosis.
Not available
S-EPMC5116738 | biostudies-literature
UnknownDistribution of tccP in clinical enterohemorrhagic and enteropathogenic Escherichia coli isolates.
Not available
S-EPMC1287796 | biostudies-literature
UnknownDistribution, functional expression, and genetic organization of Cif, a phage-encoded type III-secreted effector from enteropathogenic and enterohemorrhagic Escherichia coli.
Not available
S-EPMC2223761 | biostudies-literature
UnknownComparative genomics analysis and characterization of Shiga toxin-producing Escherichia coli O157:H7 strains reveal virulence genes, resistance genes, prophages and plasmids.
Not available
S-EPMC10731853 | biostudies-literature
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