Esteban Laura L

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Comparison of the DNA methylation profiles of CD19+ B lymphocytes of a pair of monozygotic twins discordant for common variable immunodeficiency

The methylation profiles of bisulfite-modified DNA of CD19+ cells from MZ twins discordant for CVID were compared using the Infinium HumanMethylation450 BeadChips (Illumina, Inc., San Diego, CA,). This platform allows the interrogation of >485,000 methylation sites per sample at single-nucleotide re...

ORGANISM(S): Homo sapiens

2015-06-17 | E-GEOD-63849 | biostudies-arrayexpress

NF-κB-direct activation of microRNAs with repressive effects on monocyte-specific genes is critical for osteoclast differentiation

In this study, analysis of miRNA expression changes in osteoclast differentiation from human primary monocytes revealed the rapid upregulation of two miRNA clusters, miR-212/132 and miR-99b/let-7e/125a. We demonstrate that they negatively target monocyte-specific and immunomodulatory genes like TNFA...

ORGANISM(S): Homo sapiens

2014-12-03 | E-GEOD-63773 | biostudies-arrayexpress

Impact of neuromuscular block monitoring and reversal on postoperative pulmonary complications in thoracic surgery: a Bayesian analysis of the iPROVE-OLV trial.

Not available

S-EPMC12597387 | biostudies-literature

Whole genome sequence analyses of brain imaging measures in the Framingham Study.

Not available

S-EPMC5772158 | biostudies-literature

Elevating fungal care: bridging Brazil's healthcare practices to global standards.

Not available

S-EPMC11960063 | biostudies-literature

A prognostic model for use before elective surgery to estimate the risk of postoperative pulmonary complications (GSU-Pulmonary Score): a development and validation study in three international cohorts.